Perinatal infections

Card Set Information

Author:
mariyage
ID:
127945
Filename:
Perinatal infections
Updated:
2012-01-15 13:40:53
Tags:
Perinatal ToRCHHeS drugs
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Description:
Perinatal infections and drugs
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  1. Toxoplasma gondii
    • chorioretinitis + hydrocephalus + intreacranial calcifications
    • Sulfadiazine + Pyrimethamine
  2. Rubella
    • PDA + cataracts + deafness +/- blueberry muffin rash
    • MMR vaccine (live attenuated),but not during pregnancy
  3. CMV
    • high income mothers (asxs/mono-like)
    • immunocompromised (pneumonia, retinitis,
    • latent in WBCs
    • microcephaly, hepatosplenomegaly, petechial rash
    • deafness + mental retardation (#2 after Down's)
    • Gancyclovir, Foscarnet, Cidofovir: not for baby
  4. HIV
    • recurrent infections (unresponsive to Tx) + chronic diarrhea
    • lack attainment dev'tal milestones
    • anti-retrovirals, antibiotics, IVIG
    • must screen all pregnancies
  5. HSV
    • vesicular lesions + encephalitis + neuro-ocular sequalae
    • Acyclovir IV
  6. Syphilis - Treponema pallidum
    • desquamation soles and palms + pain w limb mov't + snuffles
    • saber shins + Hutchinson's teeth + saddle nose
    • mother - Hx crack cocaine for sex
    • must sceen all pregnant women
    • Penicillin G
  7. HPV B-19
    • hydrops fetalis
    • mother - swollen joints, rash, aplastic anemia
    • kids - erythema infectiosum - slapped cheeks + fever
    • fetal blood transfusion
  8. Nisseria gonorrhea
    • during birth
    • septic arthritis + conjunctivitis
    • must scrren all pregnant women
    • Ceftriaxone - baby
    • Cephalosporin (+Azithromycin) - during pregnancy
  9. Chlamydia trichomonas
    • during birth
    • pneumonia + conjunctivitis
    • must screen all pre
    • Erythromycin - baby
    • Azithromycin, Amoxicillin - pregnancy
  10. GBS (Strep group B) - Strep agalactiae
    • sepsis + meningitis + pneumonia
    • #1 cause infectious death in newborns
    • must screen all pregnant women
    • Ampicillin
    • Penicillin prophylaxis during delivery

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