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Mechanism of Action;
competes with opioids at opiate receptor sites
respiratory depression induced by opioids, coma of unknown origin (to rule out narcotic OD)
Contraindications & Precautions;
- Contraindications; none in the emergency setting.
- Precautions; pregnancy, cardiovascular disease, opioid dependency, seizure disorder. NOTE: repeat doses of narcan may be necessary due to shorter half life than narcotics
Route and Dosage;
IV/SQ/IM; 0.4-2 mg q 2-3 min.(slow IV bolus); Peds 0.01 mg/kg
Adverse reactions and side effects;
recurrent respiratory depression
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