acetylsalicylic acid, Aspirin, ASA
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Mechanism of Action;
blocks pain impulses in CNS, reduces inflammation by inhibition of prostaglandin synthesis; decreases platelet aggregation
mild to moderate pain or fever, TIA, ischemic stroke, prophylaxis of MI, angina
Contraindications & Precautions;
- Contraindications; bleeding disorders, taking Coumadin, pediatric pts.
- Precautions; recent history of gastrointestinal bleeding or ulcers.
Route and Dosage;
MI, angina: PO 160-325 mg (Chewable tabs 81 mg, 325 mg tablets)
Adverse reactions and side effects;
GI bleeding, laryngeal edema, bronchospasm
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