Depresses the activity and reactivity of the brain stem reticular formation; does not cause significant cardiovascular or respiratory depression may cause brief apnea, slightly decreases intracranial pressure
To produce hypnosis in the process of rapid sequence intubation, induction of anesthesia.
To produce a short acting rapid hypnosis and deep sedation in awake patient needing invasive procedures (e.g. cardioversion)
Contraindications & Precautions;
Precautions; marked hypotension, severe asthma, severe cardiovascular disease
Route and Dosage:
0.3 mg/kg slow IV push; not recommended in children under age 10