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Mechanism of Action;
Depresses the activity and reactivity of the brain stem reticular formation; does not cause significant cardiovascular or respiratory depression may cause brief apnea, slightly decreases intracranial pressure
- To produce hypnosis in the process of rapid sequence intubation, induction of anesthesia.
- To produce a short acting rapid hypnosis and deep sedation in awake patient needing invasive procedures (e.g. cardioversion)
Contraindications & Precautions;
- Contraindications; Hypersensitivity
- Precautions; marked hypotension, severe asthma, severe cardiovascular disease
Route and Dosage:
0.3 mg/kg slow IV push; not recommended in children under age 10
Adverse reactions and side effects;
hypotension, myoclonus (transient skeletal muscle movements)
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