, Propanolol, Sotalol
, Nadolol, Metoprolol
**, Timolol, Atenolol
, Acebutolol, Bisoprolol, etc.
- MOA: Competitive blockade of β adrenergic receptors.
- - Some agents are specific for β1 receptors at usual doses, while others have actions on both β1 and β2 receptors
HTN. Some used also for cardiac arrhythmias, angina pectoris, glaucoma
, migraine prophylaxis, MI prevention, CHF maintenance, etc.
Many potential SDRs and D:D interactions. Individual agents need to be reviewed carefully when listed on a medication hx. Use of these agents can cause dryness or soreness of the eyes,
orthostatic hypotension, etc. Non-selective agents and high doses can exacerbate bronchospasm in asthma or COPD patients.