DIT day 4

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Author:
pszurnicki
ID:
129026
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DIT day 4
Updated:
2012-01-25 20:13:20
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DIT day
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DIT day 4
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  1. Rx for Tourettes?
    • Fluphenazine
    • Pimozide
    • Tetrabenozine
  2. WHat group of drugs cause Cushing like distribution of adipose around the trunk?
    • corticosteroids
    • HIV protease Inhibitors
  3. Homologues in Females to the females?
    Scrotum
    Prostate
    Glans Penis
    Bulbourethral Gland
    Ventral Penis
    Corpus spongiosum
    • Labia Majora
    • Urethral and Paraurethral Glands of Skene
    • Glans Clitoris
    • Bartholins Glands
    • Labia Minora
    • Vestibular Bulb
  4. 4 Drugs for HTN in pregnancy?
    • Labetalol
    • Hydralazine
    • Nifedipine
    • alpha methyl dopa
  5. 2 factors increased Digoxin Toxicity?
    • Quinidine
    • Hypokalemia
  6. Genital ulcers, rectal stricutres, intracellular gram negative bacteria?
    Lymphogranuloma venereum
  7. Testes cancer drugs?
    Eradicate
    Ball
    Cancer
    • Etoposide
    • Bleomycin
    • Cisplatin
  8. Forms a complex between Topoisomerase II and DNA?
    Etoposide
  9. Alkylates DNA, toxicity is pulmonary fibrosis?
    Busulfan
  10. Fragments DNA, Toxicity is Pulmonary Fibrosis?
    Bleomycin
  11. Blocks Purine synthesis and is metabolized Xanthine Oxidase?
    6MP
  12. Cross links DNA, nephrotoxic and ototoxic?
    Cisplatin and carboplatin
  13. Nitrogen mustard, alkylates DNA
    Cyclophosphomide/Ifofsamide
  14. FOlic acid analog that inhibits dihydrofolate reductase?
    MTX
  15. Prevents tubulin Dissambly?
    Paclitaxel
  16. Intercalates DNA and produces Oxygen free radicals and is cardiotoxic?
    Doxorubicin
  17. DNA alkylating agent used in brain cancer?
    Carmustine
  18. Prevents tubulin assembly?
    Vincristine and vinblastine
  19. Inhibits thymidate synthase?
    5FU
  20. SeRM blocks estrogen binding to ER + cells?
    • Raloxefine
    • Tamoxifene
  21. Mechanism similar to acyclovir and foscarnet?
    cytarabine
  22. Mechanism similar to fluoroquinolones?
    Etoposide
  23. Mechanism similar to trimethoprim?
    MTX
  24. Monoclonal antibody to HER-2?
    Trastuzamab
  25. Free radical induced DNA strand Breakage?
    Bleomycin
  26. Inhibitor of PRPP Synthetase?
    6MP
  27. Reversible with Leucoverin?
    MTX
  28. Treatment for Choriocarcinoma?
    • MTX
    • Vincristine/Vinblastine
  29. Treatment for AML
    Cytarabine
  30. TX for CML?
    • Busulfan
    • Imatinab
  31. Prevents breast cancer?
    • Trastuzamab
    • Tamoxifen
    • Raloxifen
  32. Rx for Testicular cancer?
    • Etoposide
    • Bleomycin
    • Cisplatin
  33. Applied topically for AK and Basal Cell carcinoma?
    5 FluoroURacil
  34. Rx for Childhood tumors?
    Rhabdomyosarcoma
    Ewings tumor
    Wilm's Tumor?
    Dactinomycin
  35. Inhibits ribonucleotide Reductase?
    Hydoxyurea
  36. SE of Hemorrhagic cystitis?
    cyclophosphoamide
  37. Antibody against Philadelphia Chromosome?
    Imatinib
  38. Side effects of Prednisone use?
    • Acne
    • Psychosis
    • cataract
    • Hypertension
    • Osteoporosis
    • Immunosuppression
    • Peptic ulcers
    • Hyperglycemia
    • Cushing-Like distribution of Body weight
  39. Most common bone tumor of children?
    Ewings sarcoma
  40. Most common bone tumor of adults?
    Osteosarcoma>Multiple Myeloma
  41. MOst common benign tumor ?
    Osteochondroma
  42. 11 to 22 Translocation?
    Ewings sarcoma
  43. Soap Bubble appearance?
    Giant cell Tumor
  44. Onion skin appearance?
    Ewings
  45. Bone tumor that may be a hamartoma?
    Osteochondroma
  46. Codman's triangle on xray?
    Osteosarcoma and pyogenic osteomyelitis
  47. Gardners syndrome tumor?
    Osteoma
  48. Hypogonadism, delayed puberty + anosomnia?
    Kallman syndrome---decreased GnRH

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