Phram. Quiz 1 part 2.txt

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  1. What is the most common source of drugs?
    Chemical Synthesis
  2. Review the chart....
    Table 1-3
  3. are central to respiratory care in pulmonary diseases. This group of drugs includes adrenergic, anticholinergic, mucoactive, corticosteroid, antiasthmatic, and antiinfective agents and surfactants instilled directly into the trachea. Other drug groups important in respiratory care include cardiovascular, antiinfective, neuromuscular blocking, and diuretic agents.
    Aerosolized agents
  4. Drugs delivered by oral inhalation or nasal inhalation are intended to provide a _____________ treatment of the respiratory tract
    local topical
  5. Aerosol doses are _______ than doses used for the same purpose and given systemically
  6. Aerosol dose Side effects are usually _____ and _______ severe with aerosol delivery than with oral or parenteral delivery
    Fewer and Less
  7. The onset of action from an aerosol is?
  8. Drug delivery is targeted to the respiratory system, with lower systemic ________
  9. The inhalation of aerosol drugs is painless, is relatively safe, and may be convenient depending on the specific delivery device used. T or F?
  10. Adrenergic agents, Antiasthmatic agents, Anticholinergic agents, Antiinfective agents, Corticosteroids, Exogenous surfactants, Mucoactive agents, Prostacyclin analogues all can be?
  11. Drugs with a low therapeutic index have?
    High toxic effect and narrow the therapeutic margin
  12. quantifies the efficiency of aerosol drug delivery to the lung and is based on the distribution to the airway and gastrointestinal tract
    lung availability/total systemic availability ratio (L/T ratio)
  13. is a drug or chemical that binds to a corresponding receptor (has affinity) and initiates a cellular effect or response (has efficacy).
  14. is a drug or chemical that is able to bind to a receptor (has affinity) but causes no response (zero efficacy).
  15. Suspension of liquid or solid particles between 0.001 and 100 micrometers (�m) in diameter in a carrier gas
  16. In reference to the size of particles in an aerosol, meaning many different particle sizes
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Phram. Quiz 1 part 2.txt
Quiz 1 part 2
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