Fever breaks, setpoint back to normal, relaxed state, fluid replacement
If healthy, not dangerous until 106.
If 106= medical emergency
If comprimised health treat earlier.
Sulfonamides ( Bactrim, Septra, Pediazole)
Can be allergic if already allergic to other sulfa drugs. Derivatives such as the sulfonomide diuretics (furosemide, acetazolmide) & oral hypoglycemics ( sulfonylureas, diabenese, macronase, glucotrol)