Ophthalmic Pharma

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Author:
Rosie435
ID:
131415
Filename:
Ophthalmic Pharma
Updated:
2012-01-29 14:17:40
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Ophthalmic Pharma
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Ophthalmic Pharma
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  1. Symp Agonist Drugs
    • Adrenaline
    • Dipivefrine
    • Phenylephrine
    • Apraclonidine
  2. Phenylephrine is Contra Indicated in
    Narrow Angle Glaucoma
  3. Adrenaline SE
    • Reactive Hyperaemia
    • Local Irritation
    • Allergy
    • Blurring of Vision
    • Conjunctiva Fibrosis
    • Cystoid Macular oedema in Aphakia
    • Systemic SE- HT, Headaches
  4. Symp Antagonists
    • B blockers
    • Guanethidine
    • Thymoxamine
  5. Non Selective B Blockers
    • Simalol
    • Timalol
    • Trigger SE in Asthma and Cardioresp diseases
  6. Selective B Blocker
    • Bitaxolol
    • Safe in asthma
  7. B Blocker SE
    • Bronchospasm
    • Cardiac Arrhythmia- esp Bradycardi
    • Depression- Rare
    • Local SE eg Allergy- V Rare
  8. Parasymp Agonisits
    • Pilocarpine
    • Carbachol
    • Acetylcholine
    • Physostigmine
    • Edrophonium
    • Phospholine Iodide
  9. Action of Pilocarpine
    • Causes Trabecular Meshwork to Open
    • V useful in Narrow Angle Glaucoma
    • Causes intense Myosis- exacerbates cataract symp
  10. Pilocarpine SE
    • Dec Visual Acquity - esp in Cataract
    • Allergy
    • Iris Cysts
    • Retinal Detachment
    • Transient Headache
    • Systemic SE:
    • - Sweating
    • - Nauesea and Vomiting
    • - Bradycardia
    • - Diarrhea
  11. Acetylcholine and carbacol Use
    • Used after surgeries with big eye incision.
    • Injected into anterior chamber
    • Constricted pupil v efficiently
    • Dec Chance of Iris Prolapse
  12. Physostigmine and Phospholine Iodide Use
    Chilren with squints
  13. Parasymp Antagonists
    • Atropine
    • Homatropine
    • Cyclopentolate
    • Tropicamide
  14. Cyclopentolate Action
    • Pupil Dilator- Onset- 30 min, Duration- 24hrs
    • Cyclopelgic- Relax Ciliary Body- Dec Pain
    • Used for Cataract surgery
    • Mild dilator and Cycloplegic agent allows pupil to move and not stick into constricted/ dilated position- useful in Uveitis
  15. Tropicamide Action
    • Dilation of Pupil
    • No cycloplegia - no loss of accomodation
    • Short Acting- 3-6 hrs
    • Out Pt Setting
  16. Atropine SE
    • Allergy
    • Fever in Children (Malignant Hyperthermia)
    • Cycloplegic- loss of accomodation and blurring
    • Systemic SE:
    • - Tachycardia
    • -Facial Flush
    • -Tremor
    • -Dry Mouth
  17. Use of Topical Steroids
    • Any inflammation in eye EXCEPT Herpes Simplex Keratitis
    • Uveitis
    • Scleritis
    • Keratitis
    • Post Op Inflam
  18. Acetazolamide- Type of drug and trade name
    • Carbonic Angydrase Inhibitor
    • Diamox
  19. Acetazolamide Uses
    • Dec IOP
    • Dec ICP
    • Mountain Sickness
    • Macular Oedema
    • Retinitis Pigmentosa
    • Glaucoma
  20. Acetaxolamide SE if used long term eg in Glaucoma
    • Parasesthesia
    • Malaise
    • Nausea
    • Loss of appetite
    • Depression
    • Hypokalaemia- give K supplements
    • Renal Stones
    • Steven Johnson's
  21. Systemic Corticosteroid SE
    Cataracts
  22. Systemic Amiodarone SE
    Corneal Deposits- Coneal Verticellosta
  23. Systemic Cholorquine SE
    Maculopathy
  24. Systemic Ethambutol SE
    Optic Neurits
  25. Systemic Chloramphenicol SE
    Disc Oedema
  26. Systemic Tetracycline
    • Papilloedema
    • Bilateral optic disc swelling but no inc IOP
  27. Systemic Steptomycin and Carbamezapine SE
    Nystagmus
  28. Systemic Metoclopramide SE
    Oculogyric Crisis

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