What are the basic actions of IL-1Beta, TNF-alpha, IL-6, CXCL8, and IL-12?
- 1. TNF-alpha - induces local inflammation and fever
- 2. CXCL8 - induces local inflammation by attracting neutrophils
- 3. IL-1Beta, IL-6 - induces fever and acute-phase response in liver
- 4. IL-12 - activates NK cells and induces differentiation of CD4 T cells into TH1 cells