BMSII-GI

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fallcloud13
ID:
131760
Filename:
BMSII-GI
Updated:
2012-01-30 21:04:37
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BMSII GI
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BMSII-GI
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  1. Cimetidine
    • H2 Antagonist
    • Famotidine>Ranitidine=Nizatidine>Cimetidine
    • Usage: GUD, PUD, GERD, Zollinger-Ellison Syndrome, Dyspepsia
  2. Omeprazole
    • PPI
    • Esomeprazole, Lansoprazoel, Rabeprazole (reversible), Pantoprazol
    • Prodrug, acid-labile, CYP2C19 inhibition, P-glycoprotein inhibition (Statin-prob), Atazanavir, azole absorp inhibition
    • Usage: GUD, PUD, GERD, Zollinger-Ellison syndrome
  3. Antacids
    • Mg(OH)2, Al(OH)3, CaCo3, NaHCO3
    • Usage: PUD
  4. Pirenzapine
    • M receptor Antagonist
    • Atropine
    • Usage: PUD
  5. Sucralfate
    • Carafate
    • Sulfated sucrose and Al(OH)3
    • Inhibits absorption of other drugs (Take 2 hrs before and after taking other drugs)
    • Usage: PUD
  6. Misoprostol
    • Cytotec
    • PGE1 analog
    • Pregnancy X
    • Usage: NASID-induced ulcers
  7. Bismuth subsalicylate
    • H. pylori
    • antidiarrheal too by inhibiting intestinal secretions
  8. Methylcellulose
    • Citrucel
    • Bulk-Forming Laxative (Dietary fiber)
    • Antidiarrhea
    • Drink a lot of water
    • GroupIII
  9. Psyllium
    • Metamucil
    • Bulk-Forming Laxative (Dietary fiber)
    • Antidiarrhea
    • Drink a lot of water
    • GroupIII
  10. Polycarbophil
    • FiberCon
    • Bulk-Forming Laxative (Dietary fiber)
    • Antidiarrhea
    • Drink a lot of water
    • GroupIII
  11. Docusate Sodium(Calcium)
    • Surfactant Laxatives
    • lowering surface tension-increase penetration of water into the feces
    • GroupIII
  12. Bisacodyl
    • Correctol, Dolcolax
    • Stimulant Laxatives (Secretory, Irritant)
    • Stimulate intestinal motility
    • GroupII
  13. Senna
    • Senokot, Ex-Lax
    • Stimulant Laxatives (Secretory, Irritant)
    • Stimulate intestinal motility
    • GroupII
  14. Castor Oil
    • Stimulant Laxatives (Secretory, Irritant)
    • Stimulate intestinal motility
    • GroupI
  15. Magnesium hydroxide
    • Phillips' Milk of Magnesia
    • Osmotic Laxatives(Saline)
    • Attract water in the lumen
    • GroupI or II
  16. Sodium phosphate
    • Fleet Phospho-Soda
    • Osmotic Laxatives(Saline)
    • Attract water in the lumen
    • GroupI or II
  17. Polyethylene Glycol
    • MiraLax
    • Osmotic Laxatives(Saline)
    • Attract water in the lumen
    • GroupI or II
  18. Lubiprostone
    • Amitiza
    • Mis. Laxatives
    • CIC-2 chloride channel opener
    • Pregnancy C
    • Group III
  19. Diphenoxylate
    • Opioids (mu and delta)
    • Decrease GI motility, secretion, Increase absorption of fluid and salt
    • Mix with Atropine to prevent abuse potential
  20. Loperamide
    • Imodium
    • Opioids (mu and delta)
    • Decrease GI motility, secretion, Increase absorption of fluid and salt
  21. Atropine
    • Anticholinergic antispasmodics
    • relieve cramping of diarrhea
  22. Ondansetron
    • Zofran
    • 5HT3 antagonists
    • Block in the CTZ and STN
    • Usage: CINV, radiation, postoperation (Antiemetic)
  23. Dexamethasone
    • Decadron
    • Glucocorticoids
    • Usage: CINV (Antiemetic)
  24. Aprepitant
    • Emend
    • NK1 antagonists
    • Block in the STN
    • Usage: CINV (Antiemetic)
  25. Prochlorperzine
    • Compazine
    • D2 antagonists
    • Blocks in the CTZ and STN
    • Usage: Usage: CINV, postoperation, General (Antiemetic)
  26. Dronabinol
    • Marinol
    • Cannabinoids agonist
    • Usage: CINV (Antiemetic)
  27. Scopolamine
    • Transderm Scop
    • Anticholinergics
    • Block M1
    • Usage: Motion Sickness (Antiemetic)
  28. Dimenhydrinate
    • Dramamine
    • Block H1 and M1
    • Antihistamines
    • Usage: Motion Sickness (Antiemetic)
  29. Graniseteron, Dolasetron
    • Kytril, Anzemet
    • 1st Gen 5HT3 receptor antagonists (Antiemetic)
  30. Palonosetron
    • Aloxi
    • 2nd Gen 5HT3 receptor antagonists (Antiemetic)
  31. Meclizine
    • Antivert
    • H1 receptor antagonists
    • Usage: Motion Sickness (Antiemetic)
  32. Promethazine
    • Phenergan
    • H1 receptor antagonist with sig. antimuscarinic activity
    • Usage: Nausea and Vomiting for Postop(Antiemetic)
  33. Alosetron
    • 5HT3 Antagonist
    • Usage: IBS-D
  34. Lubiprostone
    • CIC-2 activator
    • Usage: IBS-C
  35. Tegaserod
    • 5HT4 Agonist
    • Usage: IBS-C
  36. Cisapride
    • 5HT4 agonist
    • Usage: GERD, gastroparesis, severe chronic constipation
    • Last resort
  37. Sulfasalazine
    • 5-Aminosalicylates
    • Usage: Ulcerative colitis, Crohn's disease
  38. Mesalamine
    • 5-Aminosalicylates
    • Usage: Ulcerative colitis, Crohn's disease
  39. Predinisone
    • Glucocorticoid
    • Usage: ulcerative colitis, Crohn's disease (reduce remission)
  40. Infliximab
    • Anti-TNF-a Monoclonal antibody
    • Usage: Crohn's disease, ulcerative colitis
  41. Metoclopramide
    • D2 antagonist
    • Usage: CINV, postop NV, diabetic gastroparesis, GERD

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