Pharmacology 4

Card Set Information

Author:
svisperas
ID:
131886
Filename:
Pharmacology 4
Updated:
2012-01-31 00:56:36
Tags:
Pharmacology
Folders:

Description:
Pharmacology 4
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user svisperas on FreezingBlue Flashcards. What would you like to do?


  1. Analgesic Agents are divided into what two groups?
    • Opioids
    • Non-Opioids
  2. Non-Opioids
    • aka non-narcotic, peripheral, mild
    • Inhibit prostoglandin synthesis
    • 1. Salicylates
    • 2. NSAIDS
    • 3. Acetaminophen
  3. Opioids
    • Act on at receptor sites
    • Depress the CNS
    • Manage pain when NSAIDS are contraindicated
  4. Aspirin
    • Non-Opioid
    • Salicylates
    • Effects: Analgesic, Antipyretic, Anti-Inflammatory
  5. Tylenol
    • Non-Opioid
    • Acetaminophen
    • Effects: Analgesic, Antipyretic
    • Cannot be used as an anti-inflammatory
  6. Ibuprofen
    • Drug of choice for dental pain
    • Non-Opioid
    • NSAID
    • Effects: Analgesic, Antipyretic, Anti-Inflammatory
  7. Children doses for Aspirin
    Maximum 3.6gm / 24 hours
  8. Enteric Coated Aspirin
    • Dissolves in intestine, not stomach
    • Decrease gastric symptoms
  9. Buffer
    • Absorbed more quickly
    • Contraindicated with HBP because it contains sodium
  10. Reye's Syndrome
    • Cause is unknown
    • Associated with aspirin consumption by children
    • Also occurs in the absence of aspirin use
    • FATAL; sever brain injury
    • Hypoglycemia
  11. Ibuprofen Doses
    • 400-800mg every 4-6 hours
    • Max dose: 3.2 gm/day
    • Onset is 30 minutes
    • Duration is 4-6 hours
  12. NSAIDS should be avoided in people with...
    asthma
  13. Acetaminophen
    • Used when aspirin is contraindicated
    • Rapidly absorbed in the GI tract
    • Cannot be used as an anti-inflammatory
  14. Adverse reactions of Acetaminophen
    • Hepatic Necrosis
    • Occurs with ingestion of 20-25 gm
    • Potentially fatal at 25 gm
    • ALCOHOLICS should not use
  15. Signs of Liver Toxicity [JAUNDICE]
    Yellowish staining of the skin
  16. Staggered Overdose
    • Person repeatedly exceeds the daily recommendation through small overdoses
    • Builds up in the liver and kills the cells
  17. FDA
    • Only affects prescription drugs
    • Does not affect OTC
  18. By the FDA, prescription drugs:
    • Should be no more that 325 mg of acetaminophen per pill
    • No more than 650 mg at any one time
    • 1000mg 4xday can lead to liver toxicity
  19. Acetaminophen + Opioid =
    • Vicodin
    • Percocet
    • Lortab
    • Fioricet
    • Roxicet
  20. Which Non-Narcotic should NOT be used in the 3rd trimester?
    • Salicylates
    • NSAIDS
  21. Which Non-Narcotic is the drug of choice in pregnancy?
    Acetaminophen
  22. Which Non-Narcotic is the drug of choice during nursing?
    NSAIDS
  23. The dose of aspirin that is used to treat arthitis is 3-6gm/day
    Arthritis
  24. Strongest Opioid
    • Morphine
    • Methadone
    • Meperidine
    • Hydromorphone
  25. Intermediate Opioid
    • Oxycodone
    • Pentazocine
  26. Weakest Opioid
    • Hydrocodone
    • Codeine
    • Dihydrocodeine
    • Propoxyphene
  27. Mu stimulates:
    Analgesia
  28. Kappa stimulates:
    Dysphoria
  29. ADME
    • Absorption
    • Distribution
    • Metabolism
    • Excretion
  30. The primary and most dangerous opioid effect is:
    Respiratory Depression
  31. Constipation
    • Small doses of opioids
    • Duration outlasts analgesic effect
    • No tolerance develops
  32. Miosis
    • Pinpoint pupils
    • Important sign in diagnosing an overdose
    • Important sign in diagnosing an addict
    • No tolerance develops
  33. Urinary Retention
    • Opioids increase smooth muscle tone in urinary tract
    • Produces an anti-diuretic effect
    • Produces CNS stimulation
  34. Dysphoria
    • Mental and emotional condition in which the person experiences intense feelings of depression
    • Stimulation of Kappa
  35. Opiods stimulate the vaguyy nerve
    Vagus
  36. What cardiovascular effects are affected with high doses of opioids?
    • Hypotension
    • Bradycardia
    • Syncope
  37. Opioids can stimulate the release of histamines
    Histamines
  38. Urticaria
    • Hives
    • A skin rash
  39. Drug Dependence
    • Needs the drug to function normally
    • Stopping leads to withdrawal symptoms
  40. Drug Addiction
    • Compulsive use of the substance
    • Drug cravings
    • Continues even if the user is aware of the consequences
  41. Tolerance
    • Usually part of addiction
    • Needs higher doses each time
  42. Hydromorphone
    MORE POTENT THAN MORPHINE
  43. Meperidine
    • Demerol
    • **Little use for dentistry**
  44. Naloxone [Narcan]
    Drug of choice for treating an overdose
  45. Opioids are classified by their:
    Efficacy

What would you like to do?

Home > Flashcards > Print Preview