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Positive Symptoms:
related to behavior, thought and speech
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Negative Symptoms:
social withdrawl, lack of emotion, anergia
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Treats POSITIVE symptoms
Typical
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High Potent: (typical)
Not very sedating; Come in long acting monthly injections
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Low potent: (typical)
more sedative
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With typical you often need meds to control symptoms.
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Works on both positive and negative symptoms:
Atypical
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Dones and pines:
Atypical or typical?
Atypical
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Good for psychosis
Less neuro than traditional
- Dones and Pines (atypical)
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Generally sedating, more than dones
More metabolic symptoms
Don't need regular bloodwork
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Clonzapine is typical or atypical?
atypical
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Clonzapine causes what?
agranulocytosis
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May need side affect meds with dones, but with lesser doses.
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Positive symptoms add to your personality
Negative symptoms take away from your personality
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Positive Symptoms:
- - Agitation
- - Assualtive behavior
- - Confusion, disorientation
- - Delusions
- - Hallucinations
- - Disorganization of speech and behavior
- - Bizarre behavior
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Negative Symptoms:
- - Affective flattening
- - Alogia
- - Avolition/apathy
- - Anhedonia/asociality
- - Attentional impairment
- - Anorexia
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Limited range and intensity of emotional expression
Affective flattenting
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Restricted thought and speech
Alogia
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Lack of initiation of goal directed behavior
Avolition/Apathy
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Inability to experience pleasure or mamintain social contacts
Anhedonia/Asociality
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Inability to mentally focus
Attentional impairment
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Antipsychotic drugs work by blocking receptors of the neurotransmitter_________?
Dopamine
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Typical antipsychotics are good at treating target symptoms but with many extrapyramidal side effects.
Clozapine has a lower incidence of EPSE.
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Long acting depot injections:
- Prolixin (typical)
- Haldol (typical)
- Risperidone (atypical)
- Paliperidone (atypical)
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