anti psychotic side effects

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jtafoya
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132051
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anti psychotic side effects
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2012-01-31 17:42:56
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anti psychotic side effects
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  1. Extrapyramidal Side Effects: (3)
    - Acute Dystonia

    - Pseudoparkinsonism

    - Akathisia
  2. Treatment of extrapyramidal side effects:
    discontinue or anticholinergic
  3. Occurs in first three days.
    Acute dystonia
  4. Acute muscular rigidity and cramping

    Stiff or thick tongue with difficulty swallowing

    Laryngospasm

    Resp difficulties
    Acute dystonia signs and symptoms
  5. Treatment for acute dystonia:
    • IM or IV ANTICHOLINERGIC
    • (Cogentin or Benadryl)
  6. Acute dystonia is a medical emergency, take care of ASAP!
  7. Occurs after weeks to months.
    Pseudoparkinsonism
  8. Stooped posture

    Mask like faces

    Shuffling

    Cogwheel rigidity

    Drooling

    Tremors

    Coarse pill rolling movements
    Pseudoparkinsonism signs and symptoms
  9. Treatment of Pseudoparkinsonism
    Change medication or use an anticholinergic.
  10. Dopamine agonist for Pseudoparkinsonism symptoms
    amantadine
  11. Occurs in first 10 days.
    Akathisia
  12. Intense need to move about

    Restless or anxious

    Agitated

    Rigid posture or gait

    Lack of spontaneous gestures
    Akathisia
  13. Treatment for akathisia
    betablocker, anticholinergic, or benzo.
  14. NMS
    Neuroleptic Malignant Syndrome
  15. SEVERE! Potentially fatal reaction!
    NMS (neuroleptic malignant syndrome)
  16. Rigidity

    SUDDEN high fever

    Unstable BP, sweating, pallor

    Delirium

    Elevated CPK levels

    Confused and mute

    Agitation to stupor
    Neuroleptic Malignant Syndrome signs and symptoms.
  17. In the 1st two weeks of therapy:
    Immediate d/c of meds and supportive medical care.
  18. Treatment for neuroleptic malignant syndrome:
    • Treat the symptoms.
    • antipyretics, benzo's for anxiety, dantrolene for muscle relaxations
  19. Side affect that is life alterating change.
    Metabolic Syndrome
  20. Insulin resistance

    HTN

    High serum lipids

    Obesity

    Coagulation abnormalities
    Metabolic Syndrome
  21. Not a life threatening side effect.

    This is irreversible and does not go away!
    Tardive Dyskinesia
  22. Permanent involuntary movements
    Tardive dyskinesia
  23. Involuntary movements of:
    - tongue
    - facial and neck muscles
    - upper and lower extremities
    - tongue thrusting and protruding; lip smaking
    - blinking or grimacing
    Tardive dyskinesia
  24. Test used to check or tardive dyskinesia
    AIMS test.
  25. Side effect that causes decreased WBC
    Agranulocytosis
  26. Agranulocytosis occurs with what medication?
    Clozaril
  27. Infection

    High fever

    Chills

    Sore throat

    Malaise

    Ulceration of mucous membranes
    Agranulocytosis signs and symptoms
  28. Discontinue drug with WBC < _____?
    2000
  29. Obtain WBC weekly for 6 months.

    Then every two weeks.
  30. If baseline WBC is < ______, do not start clozaril
    3500
  31. If WBC drop less than 2000, discontinue medication.
  32. Anticholinergic side effects:
    • - Orthostatic hypotension
    • - Dry mouth
    • - Constipation
    • - Urinary hesitance or retention
    • - Blurry near vision
    • - Dry eyes, photohobia
    • - Nasal congestion
    • - Decreased memory
  33. The doctor will not usually order any medications for anticholinergic side effects.

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