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What is pruritus?
symptoms associated with many disorders (itching)
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What can produce itching?
- Histamine
- Protease
- Heat
- Cold
- Chemical
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What are Pressure Ulcers (Decubitus Ulcers)?
Ischemic ulcers resulting from pressure, shearing forces, friction, moisture
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Common sites for Pressure Ulcers
- Sacrum
- Heels
- Ischia
- Greater Trochanter
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Unrelieved Pressures
result in the endothelial cell lining capillaries becoming disrupted with platelet aggregation
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Four stages of pressure Ulcers
1-Persistant redness in light pigmented skin, persistant redness w/ blue or purple hues in dark pigment
2- Partial thickness skin loss involving the epidermis or dermis or both, Abrasion, blister, shallow crater
3-Full thickness skin loss involving damage or necrosis of subcutanous tissue : Deep Crater w/ or w/o undermining of underlying tissue
4- Full thickness skin loss with extensive destruction, tissue necrosis or damage to muscle bone or supporting structures
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Keloids
- scars that are progressively enlargeing due to excessive collagen
- shiny, hairless, elevated scars
- more common in African Americans and Orientals, ages 10-30
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When do Keloids appear?
within 1 year of trama
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Inflammatory disorders
- Allergic Contact Dermatitis
- Irritant Contact Dermatitis
- Atopic Dermatitis
- Stasis Dermatitis
- Seborrheic Dermatitis
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Allergic Contact Dermatitis
- Common form of cell mediated or delayed hypersensitivity
- s/s-Erythema, prurites, vesticles
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What may cause Allergic Contact Dermitits?
poison ivy, metals, latex
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Irritant Contact Dermatitis
- Nonimmunologically mediated inflammatino of the skin
- Severity R/T concentration and exposure time
- Lesions similar to allergic type
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What may cause Irritant Contact dermatitis?
Acids, soaps, detergents
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Atopic Dermatitis is AKA
Eczema
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Atopic Dermatitis
- more common in Infancy and childhood
- has increase serum IgE
- Family history of asthma, hay fever, atopic dermatitis
- s/s- skin is dry sensitive, itchy, skin pruritus
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Stasis Dermatitis
- occurs as a result of venous stasis and edema
- Associated with varicosities, phlebitis and vasucular trauma
- Erythema, pruritus, scaling, petechiae, hyperpigmentation, may progress to ulcerations
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Seborrheic Dermatitis
- Chronic inflammation
- on scalp, eyebrows, eyelids, ear canals, axilla, chest, back
- Infants=cradle cap
- Scaly, whitish, yellow, plaques
- Pruritus
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Papulosquamous Disorders
- Disorders charasterized by papules, scales, plaques, and erythema
- Ex-Psoriasis
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Bacterial Infections commonly caused by Staph Aureus
- Furuncles (Boils)
- Carbuncle
- Cellulitus
- Impetigo
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Furuncles
- (Boil)
- Inflammation of hair follicle, single
- Red, firm nodule that may progress to a cystic nodule
- will see pus and necrotic tissue
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Carbuncle
- Collection of infected hair follicles-multiple
- See them on back of neck, upper back, lateral thighs
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Cellulitis
- infection of dermis and subcutaneous tissue
- Extension of a skin wound, ulcer, furuncles, carbuncles
- Will see Erythema, warmth, edema, pain
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Impetigo
- caused by Staph, group A B-hemolytic streph
- Common in infants and childern-in summer season
- Vesicles and pustules weep and crust
- honey color serous liquid
- Pruritus
- Communitable
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Viral Infections (cause skin lesions)
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HSV-1
- Cold sore or fever blister
- Nongenital sites--mouth and cornea
- Vesicles rupture and form crust
- Dormant in nerve ganglia
- Recurrence stress, hormones
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HSV-2
- Genital infections
- Large number are sexually transmitted
- Vesicles that progress to ulceration
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Herpes Zoster is AKA
Shingles
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Herpes Zoster
- Varicella occurs as a primary infection followed years later by herpes zoster
- Burning pain, paresthesia localized to the affected dermatome
- Vesicular eruptions
- Find Face, cervical, thoracic dermatome
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Fungal Infection
Examples
- Tinea Corporis
- Tinea Capitis
- Tinea Pedis
- Candida
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Tinea Infection
- fungal infections of the skin and are classified according to thier location on the body
- can get from animal
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Candida
- caused by yeastlike fungus Candida Albicans
- Normally found on mucous membranes, skin , GI tract and Vagina
- s/s Burning, itching, whitich yellow curdlike substance
- ex-thrush
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Predisposing Factors to Candida
- moist warm environment
- antibiotics
- pregnancy
- cushing disease
- diabetes mellitus
- debilitated states
- <6 months of age
- Immunosuppression
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Benign Tumors
- Tumors of the skin are normally associated with aging
- Seborrheic Keratosis
- Actinic Keratosis
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Seborrheic Keratosis
- Benign proliferation of the basal cells that produce smooth or waxy elevated lesions
- more common in older adults
- on chest, back, face
- Shades of tan, yellow, flesh colored, brown-black lesions
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Actinic Keratosis
- precancerous tumors associated with exposure to UV radiation of the sun
- risk=individuals w/ unprotected light skin
- pigments patchese of rough skin
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Nevi
- Mole
- pigments and nonpigmented
- Flat and elevated
- watch for malignant transformation
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Risk Factor for skin cancer
fair complexion, excessive exposure to the sun, tanning salons, or ultraviolet radiation predisposes a person
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Basal Cell Carcinoma
- caused by sunlight exposure
- on face, neck
- slow growth
- metastatic spread rate
- more common in men then women
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Basal cell lesions..
- start as nodule
- Pearly/Ivory
- Depressed Center and rolled borders
- progressess to ulceration with waxy borders
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Squamous Cell Carcinoma
- A tumor of the epidermis
- Malignant potential
- sun exposure and fair complexion
- Red, scaly, elevated, irregular borders
- shallow chronic ulcer
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Malignant Melanoma
- A tumor originating from the melanocytes
- Rapidly progressive, metastatic
- intermittent intense sun exposure
Raised, black, brown most from Nevi or moles shades of red, blue or white
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Melanocytes
cells that synthesize the pigment melanin
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Cancer ACDE
- A=Asymmetry
- B=Border Irregularity
- C=Color variation
- D= diameter >6mm
- E=Evolving Change
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Kaposi Sarcoma
- Vascular Malignancy
- Endothelial Cell
- Purplish brown macules-develop into plaques and nodules
- Immunosuppression, transplant recipient, AIDS, African middle aged blacks, Jewish descent
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Lupus Erythematosus
- Inflammatory disease with cutaneous manifestations
- Discoid (cutaneous) is limited to the skin and can lead to SLE
- Lesions are often located on light-exposed areas of the skin, and photosensitivity is common
- most common site=face "Butterfly Rash"
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Cause of Lupus Erthematosus
altered immune responce to an unknown antigen
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Macule
- flat, circumscribed area that is a change in the color of the skin
- ex-freckle
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Papule
- An elevared firm area circumscribed are less than 1 cm in diameter
- ex-wart
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Patch
- A flat nonplable, irregular shaped macule more than 1 cm in diameter
- ex-port-wine stain
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Plaque
- Elevated, firm and rough lesion with flat top surface more than 1 cm in diameter
- ex-psoriasis
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wheal
- elevated irregular shaped area of cutaneous edema
- ex-insect bite
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Nodule
Elevated firm circumscribed lesion; deeper in dermis that a papule
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Tumor
Elevated solid lesion, may be clearly demarcated; deeper in dermis, more than 2 cm in diameter
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Vesicle
- Elevated, circumscribed superficial not into dermis, filled with serous fluid- less than 1 cm in diameter
- ex-chickpox
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Bulla
- vesticle more than 1 cm in diameter
- ex-blister
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Pustule
- elevated superficial lesion similar to a vesicle but filled with purulent fluid
- ex-acne
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Cyst
- Elevated circumscribed encapsulated lesion, in dermis or subcutaneous layer, filled with liquid or semisold material
- ex-sebaceous cyst
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Telangiectasia
- Fine, irregular red lines produced by capillary dilation
- ex- Telangiectasia in rosacea
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Scale
heaped up, keratinized cell, flaky skin, irregular thick or thin
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Lichenification
- rough, thickened epidermis secondary to persistent rubbing, itching, or skin irrritation
- ex-chronic dermatitis
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Exciriation
- loss of the epidermis, linear, hollowed out, crusted area
- ex-abrasion, scabies
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Fissure
linear crack or break from the epidermis to the dermis
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Erosion
loss of part of the epidermis, depressed, moist, glistening, follows rupture of a vesicle or bulla
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Ulcer
loss of epidermis and dermis, concave, varies in size
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Atrophy
- thinning of the skin surface and loss of skin markings, skin appears translucent and paper like
- ex=Aged skin, striae
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