Biopharmaceutics Pharmokinetics

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Author:
ba
ID:
132359
Filename:
Biopharmaceutics Pharmokinetics
Updated:
2012-02-02 00:15:05
Tags:
Equations we need know
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Description:
Equations we need to know
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  1. t1/2
    t1/2 = 0.693/K
  2. Cl
    • Cl = Vd * Ke
    • Cl = Dose/ AUC
  3. F (absolute)
    [AUC]po * dose IV divided by [AUC]IV *dose po
  4. F (relative)
    [AUC]a * dose b divided by [AUC]b dose a
  5. Db
    Db = amount of drug in the body

    Db = Vd * Cp (plasma concentration)
  6. K
    Rise over run

    k = ln C2 - ln C1 divided by t2-t1
  7. C
    C= Co* e^-kt
  8. AUC
    AUC = Co / k
  9. Vd
    Vd= dose / (AUC * K)

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