Hematology Jeopardy

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Hematology Jeopardy
2012-02-03 00:51:52
hematology pathophysiology

The study of hematology disorders through pathophysiology
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  1. What are normal values for RBCs and hemoglobin respectively?
    4.5 – 6.2 million/cu mm (mm3) andWomen - 12-16 &Men - 14-18 grams/dL
  2. What is iron deficiency anemia?
    A microcytic, hypochromic anemia (low MCV, MCH, MCHC)
  3. What is the pathophysiology of immune thrombocytopenia purpura (ITP)?
    A disorder in which antibodies usually IgG coat platelets that are then destroyed by the spleen
  4. What is acute lymphocytic leukemia (ALL)?
    Overproduction of lymphoblasts, abrupt onset, rapid progression in children
  5. What is chronic myelogenous leukemia (CML)?
    Malignant granulocytes that carry the Philadelphia chromosome.
  6. What initiates a sickle cell crisis causing anemia?
    RBC shape changes in response to dehydration, hypoxia or acidosis
  7. What are manifestations of any anemia regardless of cause?
    Tachycardia, tachypnea, dyspnea, fatigue, pale, cool extremities
  8. What are characteristics of hemoglobin F?
    Carries 8 molecules of oxygen and comprises 70% of a newborn’s blood
  9. What is an increased MCV, MCH, and MCHC?
    Indicates a large RBC and used to diagnose Vitamin B12 or folate deficiency anemias
  10. What are manifestations of aplastic anemia?
    Fever and chills; petechiae, bruising, and nosebleeds; tachycardia, tachypnea, and fatigue
  11. Hemoglobin synthesis requires this mineral
  12. What is chronic lymphocytic leukemia?
    Malignant transformation of B cells that invade lymph nodes
  13. What are manifestations of hematologic malignancies?
    Anemia, bleeding, bruising & frequent infections
  14. What is secondary polycythemia?
    Increased RBC in response to chronic hypoxia
  15. What are risk factors for vitamin B12 deficiency anemia?
    Chronic alcoholism, gastric bypass surgery, chronic atrophic gastritis
  16. What are normal values for WBCs and platelets respectively?
    5,000 - 10,000/cu mm3 and 150,000 -400,000/ mm3
  17. What manifestations would the nurse expect for a client whose platelet count is 50,000.mm3?
    Bruising and prolonged bleeding times
  18. What are manifestations for vitamin B12 deficiency
    Paresthesias of hands and feet, ataxia, vibratory sense disturbances
  19. What are manifestations of polycythemia?
    Deep vein thrombosis, splenic and hepatic congestion
  20. What are characteristics of B-cell, T-cell or NK cell lymphoma (non-Hodgkin lymphoma)?
    Originates in B-cells, T-cells or NK cells.
  21. What are characteristics of Hodgkin lymphoma?
    Malignant disorder of lymph nodes with Reed Sternberg cell, spreads in a predictable manner.
  22. What are manifestations of 40% loss of blood?
    Hypotension, tachypnea, cold, clammy skin
  23. What is pernicious anemia?
    Autoimmune disease that destroys parietal cells that produce intrinsic factor needed to absorb Vitamin B12.
  24. What is the significant of a high hematocrit (above 52%)?
    That high lab value indicates dehydration or concentrated blood.
  25. Compromises 30% of a newborn’s blood.
    Hemoglobin A
  26. What is a manifestation of folic acid anemia?
    Neural tube defect
  27. What is opisthotonus?
    The head and heel bent backward and body bowed forward.
  28. What is multiple myeloma?
    Proliferation of malignant plasma cells that infiltrate bone.