biochemistry Test one
Card Set Information
biochemistry Test one
What are the three parts of the amino acid?
Which part gives the amino acids it’s distinct structure
The R group
What is Glycene’s distinct structure group
Hydrogen is it's R group
What is a carbon with four different substitutions
asymmetrical and optically active
L amino acids are ----------- incorporated
D amino acids are made by
enzymatically made and it's sometimes ribosomally made
D amino acids have evidence that they arose by past------
In what environment is the amino acid completely protanated and what are the charges?
very low pH, the carboxylic acid and amino group have positive charges
What is the state of the amino acid at the Physiological pH and what is the Physiological pH?
The carboxylic acid will ionize by the amino acid has the hydrogen on it. and the physiological ph is a ph of 6.5
How will you be able to pull the hydrogen off the amino group? What will the charge?
by raising the
alkalinity and you will have a negative species
What is a double charge and when do you normally see them?
zwitter ion, and you normally see them in physiological pHs
What cause discourages ionization?
surrounded by hydrophobic groups
what bond encourages ionization and which bond discourages it?
Ionic bonds encourage ionization, and hydrogen bonds discourage ionization
What is the PK3?
the ionization constant of the R group
Examples of Hydrophobicity
Oil and grease
true/false R groups only have hydrophobic properties
False. R groups can have both properties of hydrophobic and hydrophilic
Globular proteins are viewed as --------- because
creme filled chocolates because they have a hydrophilic outside layer and a hydrophobic center.
What interacts with water and is responsible for the water solubility of proteins?
hydrophilic amino acids
what bonds does the hydrophilic amino acids tend to have?
ionic and hydrogen
acidic amino acids have additional ------- and where are they attached?
carboxylic acids and they are attached to the alpha carboxylic acid not the Carbon
the core part of the acidic amino acid is the------
alpha carboxylic acid
the--------is blocked so the---------stands out
alpha carboxylic acid, R group
Aspartic acid has what attached to it?
one methylated group
Glutamic acid has what attached to it?
2 methylated groups
At what pH are Aspartic and glutamic acid ionized?
What are lysosymes able to do?
they cleave carbohydrates due to the environment
the amide on aspartic acid makes it------
the amide on glutamic acid makes it-----