Endo + Gastro

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Endo + Gastro
2012-02-20 06:42:14
endocrine gastroenterology

Just the ones i answered wrong on my first proper revision day
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  1. Side effects of growth hormone therapy are?
    Manily fluid retention, oedema and injection site reactions.

    also, Gynaecomastia, benign intracranial hypertension, arthralgias.
  2. Xray appearence of Crohn's?
    • Strictures that should be discontinuous (in keeping with skip lesions)
    • Fistula formation
  3. X-ray appearence of UC?
    Lead pipe sign...

    Loss of colonic haustra

    Always continuous involvment, starting at rectum
  4. Doc...Im sweating a lot more than i used to...
    What should be going through your head?
    • Menopause
    • Thyrotoxicosis
    • Phaeo
    • Hypoglycaemia (insulinoma)
    • Acromegaly
    • TB
    • Lymphoma
    • Brucellosis
  5. Drug induced liver damage...
    Mouldy cereals and grains from west africa\southern china...
    • Methotrexate = Liver fibrosis
    • Paracetamol = Acute Hepatitis
    • Octreotide = Gall stones
    • Chlorpromazine = Acute Cholestasis
    • Mouldy cereals = Neoplasia (Aflatoxins and Mycotoxins cause p53 mutations)
  6. Drugs that cause gynaecomastia...
    • Spiro
    • Omeprazole\cimitidine
    • Digoxin
    • Furosemide
    • LHRH analogues
    • Finasteride
  7. B12 deficiency causes...?
    • Megaloblastic anaemia
    • Optic neuritis
    • Psych symptoms\ reversible dementia
    • Sensory ataxia and spastic paraparesis (SADSC)
    • Glove + Stocking anaesthesia
    • Methylmalonyl in urine (used for monitoring)
  8. Hepatitis E...Whaddya know?
    • Single stranded RNA (Hep B is the only DNA)
    • Causes acute hepatitis, Faecoral transmission
    • Causes epidemic waterborne infections
    • Never develops into chronic
    • Mortality in pregnant women = 20%!!!
  9. A 78-year-old male is brought to the Emergency Department and has a witnessed seizure in the resuscitation room.His blood glucose is recorded as 1.0 mmol/l. He does not have diabetes, and has no other significant past medical history.He is given 50 ml of 50% dextrose and he slowly recovers over the next one hour. A serum cortisol concentration later returns as 800 nmol/l (120-600). What has this pt prestented with, what can cause this presentation, how would you investigate this patient?
    • This is a case of spontaneous hypoglycaemia, which could be caused by:
    • Insulinoma
    • Insulin\sulfonylurea overdose
    • Drugs\alcohol
    • Sepsis

    In this case most likely to be an insulinoma, investigate with 72 hour fast and should another episode occur take bloods within 30mins to look for insulin+c-peptide.

    The elevated cortisol is normal considering hes having a hypo and under 'stress' conditions.
  10. 3 drugs that cause Hyperglycaemia? Apart from steroids.
    • B-blockers
    • Thiazides
    • Steroids
    • Furosemide
  11. Name 7 different types of insulin and whther they are long or short acting?
    • Humilin M3 - Mixture
    • Humalog - Fast acting
    • Actrapid - Fast
    • Novorapid - Fast
    • Inulitard - isophane - intermediate acting
    • Levemir - long acting
    • Lantis - Glargine - Long acting