Quiz 2-Chapter 3 (partial)
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Quiz 2-Chapter 3 (partial)
Which Aminoglycolside has ototoxicity and nephrotoxicity?
What is an aminoglycoside?
gram negative agents
used for serious infections
Tobrex, Tobi, TobraDex
What drug should not be used as a monotherapy to treat pneumonia?
What aminoglycoside is used to treat exacerbations in cystic fibrosis patients?
What is neosporin-polymyxin B used for?
minor skin infections
What 2 drugs are most highly effective against tuberculosis?
What are antimycobacterials?
combat mycobacterium, which have a very different cell wall anatomy than other bacteria
What is isoniazid (Laniazid, Nydrazid) used for?
treatment of active and latent TB
What are some common SE of isoniazid?
elevated liver fxn tests
What are some rare SE of isoniazid?
What drug has the common abbreviation INH?
Which antimycobacterial should be coadministered with pyridoxine (vitamin B6)? Why?
to prevent peripheral neuropathy
What is rifampin used for?
active and latent treatment of TB
treating asymptomatic carriers of Neisseria meningitides
synergistic therapy for gram+ infections like endocarditis
What are the most common SE rifampin?
elevated liver fxn tests
What are some rare SE of rifampin?
_____ is a potent inducer of many hepatic enzymes, especially the CYP450 system?
Which drug will turn your tears, urine and sweat orange/red?
Which anti-infectives were the second class of antibiotics to be developed?
Which anti-infective inhibits bacterial cell growth by inhibiting transpeptidase enzymes?
What are the common SE of all penicillins?
What are the rare SE of all penicillins?
What drug class should not be give to a patient who is allergic to cephalosporin antibiotics?
What are the main drugs which interact with penicillins?
What is amoxicillin most commonly used for?
skin and skin structure infections
H. pylori infection in gut
T/F: amoxicillin and ampicillin have the same antimicrobial spectrum.
Which has better oral absorption- amoxicillin or ampicillin?
What is augmentin used for?
upper and lower respiratory infections
mixed aerobic and anaerobic infections
How can you minimize adverse GI effects when taking augmentin?
take at start of a meal
T/F: amoxicillin has a broader antimicrobial spectrum than augmentin.
Beepen-VK, Pen-VK, Veetids
What is penicillin used for?
prophylaxis of pneumococcal infections or recurrent rheumatic fever
necrotizing ulcerative gingivitis
Which anti-infectives are beta-lactam antibiotics? (resistant to beta-lactamase enzymes)
What is the cephalosporin MOA?
inhibits bacterial cell growth in susceptible bacteria by inhibiting transpeptidase enzymes (inhibit synthesis of cell wall)
What are the most common SE of cephalosporins?
What are rare SE of cephalosporins?
bone marrow suppression
clostridium difficile-associated diarrhea
What is cefzil(cefprozil) used for?
upper and lower resp infections
What are the most common SE of cefprozil?
What is the main drug that affects cefprozil?
Cefprozil is a ____ generation cephalosporin?
If patient has PKU, what drug should they not use?
What 2 drugs can be used to treat gonorrhea, Lyme disease, UTIs and resp infections, etc?
Which drug can cause biliary sludging in neonates?
Rocephin is a _____ generation cephalosporin?
Which cephalosporin is available as both IV injection and oral tab/suspension?
What is cephalexin used for?
Cephalexin is a _____ generation cephalosporin?
T/F: cephalexin is effective against MRSA.
T/F: all fluoroquinolones are available IV and orally.
Name 3 fluoroquinolones.
Name a glycopeptide.
What are common SE of vanco?
"Red Man's syndrome" (rash, flushing, tachycardia, hypotension)
Which drug can affect the actions of anesthesia?
can enhance histamine release and rash
What is the drug of choice for treating MRSA?
There is only one commonly used lincosamide. What is it?
T/F: clindamycin can be used to treat some strains of MRSA.
Which antibiotic can actually cause psuedomembranous colitis instead of treat it?
Zithromax, Zmx, Z-pak
Biaxin, Biaxin XL
Ery-Tab, E-Mycin, EES, Ilosone, EryPed
What are some macrolides?
Which macrolide is used off-label for motility?
What is the only common nitroimidazole used?
What is flagyl used for?
anaerobic infections (mostly)
C. difficile infections
pelvic inflamm disease
GI surgery prophylaxis
Which drug has a common SE of metallic taste?
Name a folic acid antagonist (sulfonamide as well)
Which antibiotic can be used to treat traveller's diarrhea?
Which antibiotics are the drug of choice for tick-borne diseases?
Which antibiotic can cause tooth discoloration if used too long?
Which antibiotics may render oral contraceptives less effective?
Which drug must be thrown out if therapy is complete and do not use outdated because it could cause Fanconi syndrome (kidney damage)?
What drug can treat Rocky Mountain spotted fever, typhus fever, Lyme disease, plague, tularemia, Q fever, rickettsialpox?
doxycycline (or minocycline)
What are 2 tetracyclines?
What is the only nitrofuran?
What is the antibiotic of choice for a UTI that is resistant to bactrim, septra, cipro, levaquin, or avelox?
T/F: nitrofurantoin should not be used for any other infection other than uncomplicated cystitis.
T/F: nitrofurantoin can be used in pregnant women.
Which antibiotic will give a false positive on a urine glucose test?