RT 185 Pathology
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Define Legg-Calve-Perthes disease:
A hip disorder in children due to interruption of the blood supply to the head of the femur.
Most common at age 6-9, more severe in girls.
Form of arthritis marked by chronic cartilage deterioration in synovial joints & vertebrae.
Common in middle aged people.
Define rheumatoid arthritis:
Chronic autoimmune disease that causes inflammation and deformity of the joints.
Common in women.
Define osteogenic sarcoma:
Malignant bone tumor; most common in children and young adults where it tends to affect the femur or long end of bones.
Common in the 10-25 age group.
Loss of bone density.
Most common in post-menopausal women.
Define Osgood-Schlatter disease:
Irritation of the patellar tendon at the tibial tuberosity.
Commonly affects active young people, particularly boys between the ages of 10 and 15.
Define ankylosing spondylitis:
Inflammation or fusing of the joints in the spine.
Most common in males 30 years old and older.
Define Paget's disease:
Chronic disease of bone that fractures easily.
Rarely diagnosed in people under 40. Men and women are affected equally.
Define osteogenesis imperfecta:
Brittle bone disease.
Affects equal numbers of males and females.
Define multiple myeloma:
Cancer of the plasma cells in bone marrow.
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