Test 2 Drugs

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    Cefazolin

    First Generation

    Parenteral
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    Cefadroxil

    First Generation

    Oral
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    Cephalexin

    First Generation

    Oral
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    Cefotetan

    Second Generation

    Parenteral

    Hypothromobinemia
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    Cefoperazone

    Third Generation

    Parenteral

    Higher Hepatic Elimination

    Pseudocholelithiasis
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    Cefuroxime axetil

    Second Generation

    Parenteral or Oral

    Prodrug
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    Cefoxitin

    Second Generation

    Parenteral
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    Cefaclor

    Second Generation

    Oral

    Rash
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    Ceftaroline Fosamil

    Fifth Generation

    Parenteral

    Prodrug
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    Penicillin G

    Natural Penicillin

    Oral, IV, IM

    Free acid for oral only, Na and K for all three

    Procaine and Benzathine

    SJS, TEN, Seizures
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    Penicillin V

    Natural Penicillin

    Oral (Na and K)
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    Methacillin

    Antistaphylococcal Penicillin
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    Nafacillin

    Antistaphylococcal Penicillin

    Mainly IV (Na and K)

    Hepatic elimination

    Increased serum transaminases
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    Dicloxacillin

    Antistaphylococcal Penicillin

    Oral (Na)
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    Cloxacillin

    Antistaphylococcal Penicillin

    Oral (Na)
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    Oxacillin

    Antistaphylococcal Penicillin

    Oral, IM, IV (Na)

    Increased serum transaminases
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    Ampicillin

    Aminopenicillin

    Mainly IV (Na)

    Emergency

    CDAD, Rash, SJS, TEN
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    Amoxicillin

    Aminopenicillin

    Oral

    Rash
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    Ceftazidime

    Third Generation

    Parenteral
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    Cefixime

    Third Generation

    Oral
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    Ceftibuten

    Third Generation

    Oral
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    Cefdinir

    Third Generation

    Oral
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    Cefditoren Pivoxil

    Third Generation

    Oral

    Prodrug
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    Cefpodoxime Proxetil

    Second Generation

    Oral

    Prodrug
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    Cefprozil

    Second Generation

    Oral

    Rash
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    Cefotaxime

    Third Generation

    Parenteral
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    Ceftriaxone

    Third Generation

    Parenteral

    Higher Hepatic Elimination

    Pseudocholelithiasis
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    Cefepime

    Fourth Generation

    Parenteral
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    Carbenicillin

    Carboxypenicillin (ESP)
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    Ticarcillin

    Carboxypenicillin (ESP)

    IM, IV (DiNa)

    Anticoagulation, Na overload (Hypokalemia)

    Not as effective as Piperacillin
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    Piperacillin

    Urcidopenicillin

    IM, IV (Na)
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    Sulbactam

    Ampicillin - Sulbactam (IV)
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    Clavulanic Acid

    Amoxicillin - Clavulanate (Oral)

    Ticarcillin - Clavulanate (IV)

    Hepatotoxicity
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    Tazobactam

    Piperacillin - Tazobactam
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    Aztreonam

    Usually not given alone

    Inhalation form avaliable (sickle cell)
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    Ertapenem

    Carbapenem

    Don't use for Psuedomonads
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    Doripenem

    Carbapenem
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    Meropenem

    Carbapenem

    Works on B. cepacia
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    Imipenem

    Carbapenem

    Given with Cilastatin

    Seizures (don't use for meningitis), GI problems
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    Vancomycin

    Glycoprotein

    Treats CDAD, MRSA/E, and PRSP

    Causes Red Man Syndrome
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    Daptomycin

    Lipopeptides

    Severe GI problems, Rhabdomyolysis
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    Televancin

    Lipoglycopeptide

    QT prolongation, Avoid in pregnancy, Effects INR, Red Man Syndrome
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133606
Card Set
Test 2 Drugs
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Test 2 Drugs
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