Test 2 Drugs

Cefazolin

First Generation

Parenteral

Cefadroxil

First Generation

Oral

Cephalexin

First Generation

Oral

Cefotetan

Second Generation

Parenteral

Hypothromobinemia

Cefoperazone

Third Generation

Parenteral

Higher Hepatic Elimination

Pseudocholelithiasis

Cefuroxime axetil

Second Generation

Parenteral or Oral

Prodrug

Cefoxitin

Second Generation

Parenteral

Cefaclor

Second Generation

Oral

Rash

Ceftaroline Fosamil

Fifth Generation

Parenteral

Prodrug

Penicillin G

Natural Penicillin

Oral, IV, IM

Free acid for oral only, Na and K for all three

Procaine and Benzathine

SJS, TEN, Seizures

Penicillin V

Natural Penicillin

Oral (Na and K)

Methacillin

Antistaphylococcal Penicillin

Nafacillin

Antistaphylococcal Penicillin

Mainly IV (Na and K)

Hepatic elimination

Increased serum transaminases

Dicloxacillin

Antistaphylococcal Penicillin

Oral (Na)

Cloxacillin

Antistaphylococcal Penicillin

Oral (Na)

Oxacillin

Antistaphylococcal Penicillin

Oral, IM, IV (Na)

Increased serum transaminases

Ampicillin

Aminopenicillin

Mainly IV (Na)

Emergency

CDAD, Rash, SJS, TEN

Amoxicillin

Aminopenicillin

Oral

Rash

Ceftazidime

Third Generation

Parenteral

Cefixime

Third Generation

Oral

Ceftibuten

Third Generation

Oral

Cefdinir

Third Generation

Oral

Cefditoren Pivoxil

Third Generation

Oral

Prodrug

Cefpodoxime Proxetil

Second Generation

Oral

Prodrug

Cefprozil

Second Generation

Oral

Rash

Cefotaxime

Third Generation

Parenteral

Ceftriaxone

Third Generation

Parenteral

Higher Hepatic Elimination

Pseudocholelithiasis

Cefepime

Fourth Generation

Parenteral

Carbenicillin

Carboxypenicillin (ESP)

Ticarcillin

Carboxypenicillin (ESP)

IM, IV (DiNa)

Anticoagulation, Na overload (Hypokalemia)

Not as effective as Piperacillin

Piperacillin

Urcidopenicillin

IM, IV (Na)

Sulbactam

Ampicillin - Sulbactam (IV)

Clavulanic Acid

Amoxicillin - Clavulanate (Oral)

Ticarcillin - Clavulanate (IV)

Hepatotoxicity

Tazobactam

Piperacillin - Tazobactam

Aztreonam

Usually not given alone

Inhalation form avaliable (sickle cell)

Ertapenem

Carbapenem

Don't use for Psuedomonads

Doripenem

Carbapenem

Meropenem

Carbapenem

Works on B. cepacia

Imipenem

Carbapenem

Given with Cilastatin

Seizures (don't use for meningitis), GI problems

Vancomycin

Glycoprotein

Treats CDAD, MRSA/E, and PRSP

Causes Red Man Syndrome

Daptomycin

Lipopeptides

Severe GI problems, Rhabdomyolysis

Televancin

Lipoglycopeptide

QT prolongation, Avoid in pregnancy, Effects INR, Red Man Syndrome