P.chem 1b

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Author:
christian.deniega
ID:
133791
Filename:
P.chem 1b
Updated:
2012-02-08 16:58:54
Tags:
midterms
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Description:
acronym (anti-neoplastics)
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  1. TK
    Tyrosine kinase Inhibitor
  2. TNM
    • T - tumor
    • N - lymph node involvement
    • M - metastasis
  3. CDKs
    Cyclin-dependent kinases
  4. Rb
    Retinoblastoma protein
  5. MMR
    Mismatch Repair
  6. BCNU
    Carmustine
  7. MTIC
    Monomethyl triazeno imidazole caroxamide
  8. MOPP
    • Mechlorethamine (aka HN2 or Mustargen)
    • Oncovin (vincristine)
    • Procarbazine
    • Prednisone
  9. NSCLC
    Non-small cell lung cancer
  10. CML
    Chronic myelogenous leukemia
  11. AGAT
    O-6-alkylguanine phosphoribosyl transferase
  12. 5-FU
    5-Fluorouracil
  13. TS
    Thymidylate synthase
  14. DPD
    Dihydropyrimidine dehydrogenase
  15. CDHP
    5-chloro-2,4-dihyroxypyridine
  16. 6-MPMP
    6-thioinosinate
  17. TPMT
    Thiopurine-S-methyl-transferase
  18. XO
    Xanthine oxidase
  19. GARFT
    Glycinamide ribonucleotide formyl transferase
  20. DHFR
    Dihydrofolate reductase
  21. IRP-1
    Iron regulatory protein-1
  22. MLL
    Mixed lineage leukemia
  23. ALL
    Acute Lymphoblastic Leukemia
  24. MAPs
    Microtubule-associated proteins
  25. MDR
    Multidrug resistance
  26. Pgp
    Permeability glycoprotein
  27. MRP1
    Multidrug resistance protein
  28. ABVD
    • Adriamycin
    • Bleomycin¬†
    • Vinblastine
    • Dacarbazine
  29. SH2
    Src homology 2 domain
  30. MAPK
    Mitogen activated protein kinase
  31. EGF
    Epidermal growth factor
  32. PDGF
    Platelet-derived growth factor
  33. NGF
    Nerve growth factor
  34. VEGF
    Vascular Endothelial growth factor
  35. SCF
    Stem cell factor
  36. GFL
    Glial cell line-derived neurotropic factor
  37. RCC
    Renal Cell Carcinoma
  38. GIST
    GI stomal tumors
  39. BCRP
    Breast Cancer resistance protein
  40. HDACis
    Histone deacetylase inhibitor
  41. PML
    Promyelocytic leukemia
  42. RAR
    Retinoic acid receptor
  43. CRAPBs
    Cellular retinoic acid-binding proteins
  44. HAT
    • Hypoxanthine
    • Aminopterin
    • Thymidine
  45. HER2
    Human Epidermal growth factor receptor type 2
  46. ADCC
    Antibody-mediated cellular cytotoxicity
  47. CEA
    Carcinoembryonic antigen
  48. TAG
    Tumor-associated glycoprotein
  49. PSMA
    Prostate surface membrane antigen

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