What is the ground substance of cartilage made of?
Glycosaminoglacans ( GAGs ) are long-chained polysacharides that attach to a core protein. They are anionc, negatively charged and hydrophilic, attract water. These GAGs attach to a protein core to form Proteoglycans.
The proteoglycans ( GAGs around a core protein ) are attached to hyaluronic acid, an even bigger mollecule, several of them on an acid, sort of like rows of bottle brushes attached to the acid to form Proteoglycan Aggregates.
The aggregates form linkages with collagen fibrils.
Chondronectin is a protein that links the collagen fibrils to other proteins in the cell membranes of cartilage cells.