MSII Test 1 part 2

fight bacterial infections, most numerous, 60% of all WBC

combat parasitic infections and are associated with allergic reactions and other inflammatory processes

initiates a massive inflammatory response that brings other WBCs to site of infection; work with IgE which triggers basophils to release histamine

circulate in the blood and then enter tissue; can survive for months to years

coordinate actions of other immune cells via CSF; increase in diverse infections and immune responses

to determine whether cell mediated immune functions are normal

used to detect and identify microorganisms in the stool

when neutrophils are >60% and indicates that bone marrow has been stimulated to produce more neutrophils to fight off infection

(%neutro + %bands) X WBC

lung, blood, skin, urinary tract and GI tract

high doses of chemo (inductions)

mediated by IgE reacting to common allergens, such as dust, pollen

mediated by antibody reactions like with mismatched blood transfusion or response to various drugs

some autoimmune reactions, occupational diseases, or response to various drugs

delayed reactions, TB skin testing, contact dermatitis

secrete histamine and heparin

stuck on blood vessel in connective tissue near capillary

Mast cells stay put

5-10K

will mask symptoms instead of show disease

penicillin

illness, vaccination, permanent

snake bite (immunoglobin injection), breastmilk or placenta

non specific, 24/7, skin and mucous membranes, inflammation

active-only when needed

temporary

maintain fluid balance, protect body from infection and disease

clear, colorless fluid similar to plasma but much mess protein (albumin), originates as tissue fluid

blood

on all mucous membranes-prevents bacteria from attacking to mucous membranes; passed on in mother�s milk

passed through placenta

B cell

T c

created by plasma cells

attacks specific antigen

IgG (majority of immunoglobins)

bone marrow

inflammatory

both suppress bone marrow

bleeding and infection

viruses, not bacteria

enhance phagocytosis

humoral/antibacterial and cell mediated

initiated when IgM on B lymphocytes detect a foreign antigen; can be active or passive

aimed at intracellular defects caused by viruses and cancer-T cells destroy defective cell; responsible for delayed hypersensitivity reactions and rejection of transplanted tissue

produce IgM

produce IgG

kills whole cell

decreased production (chemo, radiation, matastic cancer) and increased destruction (medication induced, viral disease, bacterial infections)

inflammation of mucous membranes in the mouth

liver, brain, bone, lungs

Prostate and Breast

lung and bronchus

Cell appears somewhat abnormal but continues to function normally

Latent period before increased growth forms tumors

Tumor development-cells mutate

Transformed cells relocate by direct extension, invasion, establishment of remote cites

Fibrous connective tissue

Fat tissue

Smooth muscle tissue

Skin, glands, linings or digestive, urinary, respiratory tracts

Bone, muscle, other connective tissue

Pigment cells in the skin

Blood forming tissues-lymphoid, plasma, bone marrow

asymmetry, border, color, diameter

change in bowel or bladder,a sore that does not heal, unusual bleeding, thickening of lump in breast, indigestion or difficulty swallowing, obvious change in wart or mole, nagging cough

by the blood and lymph

T=tumor, N-regional lymph nodes, M-distant metastasis

Escape of fluid or blood from a blood vessel into body tissue

stimulate the bone marrow to produce platelets, red and white blood cells

produces erythrocytes

communicate with cells

high WBC count, but immature and nonfunctioning cells

series of cellular changes that signal the body�s response to injury or infection

anti-inflammatory substance that slows release of histamine, prevents influx of leukocytes, stabilizes lysosomal membranes

infections-infection is a specific process

Causative agent, reservoir, portal of exit, mode of transfer, portal of entry, mode susceptible host

iatrogenic infection