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What genetic disorder of horses involves the failure of functional B and T lymphocyte production and results in the death of a foal (adenovirus) before 5 months of age?
What are some responses to injury of the thymus?
- Lymphoid atrophy
- Hemorrhage and hematomas
What are some degenerative disorders of the thymus?
- Chemotherapeutic agents and radiations
What are some viruses that can cause thymus degeneration?
- Canine distemper virus
- EHV-1 in aborted foals
- Feline parvovirus
What are some toxins that can cause degeneration of the thymus?
- Halogenated aromatic hydrocarbons
- Fumonisins B1 and B2
- Aflatoxins (pigs)
What type of lymphoma is usually seen in the cranial mediastinum of beef cattle (6-24 months)?
Bovine thymic lymphoma
What type of lymphoma is usually seen as white or gray mediastinal masses in the cat with pleural fluid accumulation?
Feline thymic lymphoma
What type of benign neoplasia is a tumor of epithelial cells arising in the cranial mediastinum of older animals?
What is the etiology behind dogs suffereing from thymic hemorrhage and hematomas?
- Rupture of dissecting aortic aneurysms
- Trauma from automobile accidents
- Ingestion of rodenticides
What etiologies can cause congestion leading to uniform "bloody" spleen?
- Barbiturate euthanasia
- Electric stunning of pigs
What etiologies can cause acute hyperemia leading to uniform "bloody" spleen?
What etiologies can cause acute hemolytic anemias leading to uniform "bloody" spleen?
- Equine infectious anemia
What are some conditions that lead to a uniform splenomegaly with a "meaty" consistency?
- Bacteremias and low grade septicemias
- Chronic infectious diseases
- Prolonged hemolytic anemias
- Lymphoid hyperplasia
- Stored deposits of material (lysosomal and amyloid)
- Extramedullary hematopoiesis
- Splenic myeloid metaplasia
What are some conditions that can lead to splenic nodules with a bloody consistency?
- Hematomas induced by lymphoid hyperplastic nodules
- Hematomas induced by splenic vascular neoplasms
- Incompletely contracted areas of the spleen
- Vascular neoplasms
- Acute splenic infarcts
What condistions can lead to splenic nodules with a firm consistency?
- Nodular hyperplasia
- Primary neoplasms
- Metastatic neoplasms
What are some conditions that can lead to small spleens?
- Deveolomental anomalies (immunodeficiency diseases and accessory spleens)
- Aging changes (lymphoid atrophy
- Wasting and or cachetic disease (starvation)
- Splenic contraction
What developmental disorder results in hypoplasia of lymph nodes and an immunodeficiency in dogs and horses?
What condition is usually due to regional LN draining an inflammatory site and becoming infected?
What type of lymphadenitis is usually caused by Corynebacterium psudotuberculosis with abscess formation?
Chronic suppurative lymphadenitis
What type of lymphadenitis is usually caused by tuberculosis (Mycobacterium) in pigs and cattle or bovine Johne's disease?
Focal granulomatous lymphadenitis
What type of lymphadenitis is usually caused by blastomycosis, cryptococcosis, and demodicosis (Demodex foreign body)?
Focal coalescing granulomatous lymphadenitis
What type of lymphadenitis is usually caused by histoplasmosis (Histoplasma capsulatum) and Leishmaniasis?
Diffuse granulomatous lymphadenitis
What is the most common neoplasm of lymph nodes?
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