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What genetic disorder of horses involves the failure of functional B and T lymphocyte production and results in the death of a foal (adenovirus) before 5 months of age?
Equine CID
What are some responses to injury of the thymus?
Lymphoid atrophy
Neoplasia
Hemorrhage and hematomas
What are some degenerative disorders of the thymus?
Viruses
Toxins
Chemotherapeutic agents and radiations
Malnutrition
Aging
What are some viruses that can cause thymus degeneration?
Canine distemper virus
EHV-1 in aborted foals
Feline parvovirus
FIV
BVDV
HC
What are some toxins that can cause degeneration of the thymus?
Halogenated aromatic hydrocarbons
Fumonisins B1 and B2
Aflatoxins (pigs)
What type of lymphoma is usually seen in the cranial mediastinum of beef cattle (6-24 months)?
Bovine thymic lymphoma
What type of lymphoma is usually seen as white or gray mediastinal masses in the cat with pleural fluid accumulation?
Feline thymic lymphoma
What type of benign neoplasia is a tumor of epithelial cells arising in the cranial mediastinum of older animals?
Thymoma
What is the etiology behind dogs suffereing from thymic hemorrhage and hematomas?
Rupture of dissecting aortic aneurysms
Trauma from automobile accidents
Ingestion of rodenticides
What etiologies can cause congestion leading to uniform "bloody" spleen?
Torsion
Barbiturate euthanasia
Sedation
Electric stunning of pigs
What etiologies can cause acute hyperemia leading to uniform "bloody" spleen?
Septicemia
Inflammation
Anthrax
What etiologies can cause acute hemolytic anemias leading to uniform "bloody" spleen?
Babesiosis
Equine infectious anemia
What are some conditions that lead to a uniform splenomegaly with a "meaty" consistency?
Bacteremias and low grade septicemias
Chronic infectious diseases
Prolonged hemolytic anemias
Lymphoid hyperplasia
Neoplasia
Stored deposits of material (lysosomal and amyloid)
Extramedullary hematopoiesis
Splenic myeloid metaplasia
What are some conditions that can lead to splenic nodules with a bloody consistency?
Hematomas induced by lymphoid hyperplastic nodules
Hematomas induced by splenic vascular neoplasms
Incompletely contracted areas of the spleen
Vascular neoplasms
Acute splenic infarcts
What condistions can lead to splenic nodules with a firm consistency?
Nodular hyperplasia
Primary neoplasms
Metastatic neoplasms
Granulomas
Abscesses
What are some conditions that can lead to small spleens?
Deveolomental anomalies (immunodeficiency diseases and accessory spleens)
Aging changes (lymphoid atrophy
Wasting and or cachetic disease (starvation)
Splenic contraction
What developmental disorder results in hypoplasia of lymph nodes and an immunodeficiency in dogs and horses?
SCID
What condition is usually due to regional LN draining an inflammatory site and becoming infected?
Acute lymphadenitis
What type of lymphadenitis is usually caused by Corynebacterium psudotuberculosis with abscess formation?
Chronic suppurative lymphadenitis
What type of lymphadenitis is usually caused by tuberculosis (Mycobacterium) in pigs and cattle or bovine Johne's disease?
Focal granulomatous lymphadenitis
What type of lymphadenitis is usually caused by blastomycosis, cryptococcosis, and demodicosis (Demodex foreign body)?
Focal coalescing granulomatous lymphadenitis
What type of lymphadenitis is usually caused by histoplasmosis (Histoplasma capsulatum) and Leishmaniasis?