Senile Calcific Aortic Stenosis
- Both upper and lower panels exhibit the same aortic valve as viewed from top.
- The upper panel shows the aortic valve when it is closed as in diastole. You can appreciate a significant number of heaped-up calcified masses mostly at the bases of the aortic cusps protruding through the outflow surfaces into the sinus of Valsalva. Also, there is no commissural fusion as in rheumatic heart disease, which is another potential cause for aortic stenosis.
- The lower panel shows the aortic valve when it is opened as in systole. You can see that the calcified masses are preventing the valve cusps from opening completely resulting in obstruction to flow.
- -calcification on valves > stenosis; yet valves can close properly, so there is little leakage
- -problem: once pts get symptomatic, mortality is very high; there is no contraindication to surgery for treatment
- -new therapy: insertion of artificial heart valve; valve replacement