Extractions

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Author:
abbyljones9
ID:
135237
Filename:
Extractions
Updated:
2012-02-26 20:44:40
Tags:
Drug Analysis
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Description:
Test #2
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  1. Define

    amphoteric
    A compound which contains both acidic and basic functional groups
  2. Define

    solubility
    • The capacity of two or more substances to form, without chemical reaction, a homogenous molecular dispersion
  3. Define

    Acid
    A compound which can donate a proton
  4. Define

    Base
    A compound which can accept a proton
  5. Define

    solvent
    the liquid componet into which the solute is dissolved
  6. Name one source where chemical information, such as solubility, melting points, etc, can be found.
    Merck index or Clark's

    isolation and identification of drugs
  7. Name 3 types of extractions.
    • Dry Extractions
    • • Liquid-Liquid extractions
    • • ANOR Extractions
  8. Name 2 of the common solvents used in extractions.
    • chloroform
    • diethyl ether
    • petroleum ether
    • ethyl acetate
  9. What extraction technique can be used specifically for methamphetamine and amphetamine?
    What chemical property makes this extraction work?
    • Alkaline Diffusion
    • Takes advantage of the volatile nature of a drug in its base form
  10. Drugs in the basic (ionic) state tend to be __________ in water while their salt forms tend to be __________ in water.
    • insoluble
    • soluble
  11. True or False

    Sugars are typically soluble in organic solvents.
    True
  12. True or False

    Tablet binders are typically insoluble in organic sovents.
    True
  13. True or False

    When determining solubility based on polarity, the general rule that can be applied is "like dissolves like".
    True
  14. True or False

    Liquid-liquid extractions are the simplest type of extractions.
    False

    Dry extractions
  15. What is a solute?
    The compound that is dissolved in a liquid solvent
  16. True or False

    Cocaine base is soluble in petroleum ether, and cocaine HCl is soluble in chloroform.
    True

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