Inheritance types

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polymorphism

gene variant is in less than 1% of population
Sex-linked
- inheritance of genes that are unique to a sex chromosomes
- pseudoautosomal genes – genes on both sex chromosomes appear to be on autosomes
Sex-influenced
- An allele is expressed differently in each sex.
- Behaving dominantly in one sex and recessively in the other
Sex-limited

An allele is only expressed in one or the other sex
gene dosage effect
allelic series

Dominance hierarchy will exist for multiple alleles
Lethal alleles
- versions of genes w/potential to cause the death of the organism
- typically mutations in essential genes
- recessives and dominant inheritance patterns
Nonessential genes
- are those not absolutely required for survival
- mutation deleterious
Essential genes
- are those that are absolutely required for survival
- The absence of their protein product leads to a lethal phenotype
- It is estimated that about 1/3 of all genes are essential for survival