Sem 2, mini 1 pharm tx

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Author:
sweetlu
ID:
136284
Filename:
Sem 2, mini 1 pharm tx
Updated:
2012-02-19 10:06:56
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Sem mini pharm tx
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Description:
Sem 2, mini 1 pharm tx
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  1. Schizophrenia
    • - altered DA neuronal function
    • - high in some areas low in others
    • - Tx- antipsychotics, working on DA, Ser and Glutamate
    • -haloperidol, or a glutamate antagonist
  2. Bipolar disorder
    • - often linked to use of drugs that treat schizophrenia
    • - mania is caused by too much DA
  3. Depression
    • - low Ser and other monoamines
    • - fluoxetine- Ser uptake inhibitor
  4. ADD
    • -low DA and/or NE in the cortex
    • - amphetamine(DA), clonidine and guafacine (NE)
  5. anxiety
    • - treated by enhancing GABA A channels
    • - barbituates and benzodiazepines(benzo-> dec suicide risk)
  6. Sleep disorders
    - altered GABA A function
  7. Pain
    • - treatment targeted at decreasing repeated neuronal firing
    • - NE, opiod and siezure meds
  8. Epilepsy
    • - excessive neuronal firing
    • - drugs that enhance GABA, that block ion channels
  9. Degenerative disorders
    AD- cholinergic system loss

    Parkinsons- DA system lost

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