Neuropath - Congenital Malformations

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  1. What are the basic categories of central nervous system congenital malformations?
    • Dorsal Induction
    • Ventral Induction
    • Hindbrain Patterning
    • Proliferative / Migrational
    • Destructive
  2. Disorders of Dorsal Induction include
    • Failure of Neuropore Closure:
    • - Craniorachischisis (total)
    • - Anencephaly (anterior)
    • - Myeloschisis (posterior)

    • Failure of Mesoderm Closure:
    • - Encephalocele
    • - Meningoceole

    • Occult Dysraphism:
    • - Myelocystoceole
    • - Meninoceole
    • - Diastematomyelia
    • - Diplomyelia
    • - Tethered Cord
    • - Spina Bifida Occulta
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    Cranioraschisis Totalis
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    Posterior Encephaloceole
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    Anencephaly
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    Encephaloceole
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    Spinal Dysraphism

    Likely myelomeningoceole
  8. Abnormalities in Ventral Induction include
    Failure of Formation: Aprosencephaly and Atelencephaly

    Failure of Cleavage: Holoprosencephaly (alobar, semilobar, or lobar)

    Failure of Midline Development (Septooptic Dysplasia, Agenesis of the Corpus Callosum)
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    Alobar Holoprosencephaly
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    Cyclopsia as seen in holoprosencephaly
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    Agenesis of the Corpus Callosum
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    Alobar Holoprosencephaly
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    Semilobar Holoprosencephaly
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    Lobar Holoprosencephaly
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    Agenesis of the Corpus Callosum
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    Colpocephaly
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    Closed Lip Schizencephaly
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    Schizencephaly
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    Hydranencephaly
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    Porencephaly
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    Open Lip Schizencephaly
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    Lisencephaly
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    Type 1 Lissencephaly
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    Type I Lissencephaly
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    Type II Lissencephaly
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    Type II Lissencephaly
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    Polymicrogyria
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    Polymicrogyria
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    Perisylvian Syndrome
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    • Dandy Walker Malformation
    • - Vermal Hypogenesis
    • - High-riding tentorium
    • - Posterio Cranial Fossa Cyst
  31. Disorders of Hindbrain Patterning include:
    • Dandy Walker Malformation
    • Rhomboencephalosynapsis
    • Joubert Syndrome
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    Molar Tooth Sign as seen in Joubert Syndrome
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    Hemimegalencephaly
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    Hydrocephalus
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    Porencephaly
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    Hydranencephaly
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    Chiari Malformation
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    Dandy Walker Malformation
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    Intraventricular Hemorrhage
Author
ID
136693
Card Set
Neuropath - Congenital Malformations
Description
Pathology slides showing common congenital malformations
Updated
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