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Meeting 2
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plasma membrane (any membrane)
has 2 functions:
1) to act as a barrier
2) but things have to pass through/be transported through as well...this is what proteins are good for
lipid-anchor protein
polypeptides of interest aren’t hydrophobic in any
way but attach to the membrane using lipid anchors; anchors don’t span whole membrane; the peptides are functional only on ONE side of membrane
peripheral membrane protein
not covalently bonded to membrane; located at and are functional at the membrane; attached via weak interactions w/ head groups
integral membrane protein
proteins that span the whole membrane and bridge between the 2 sides; essential for bridging exoplasmic & cytoplasmic
-have both hydrophobic (for internal) and hydrophilic residues (to interact w/ head groups)
hydrophobic amino acids:
aliphatic (cyclic) ones are extremely hydrophobic (3 out of the 8); these are the ones that can interact with fatty acids (especially cholesterol)
-basically all those CH
3
's are good for fatty acid interactions
micelle's v. liposomes
micelle's have no internal acques compartment; liposomes do
Author:
mse263
ID:
137093
Card Set:
Meeting 2
Updated:
2012-02-24 17:42:17
Tags:
MCBII
Folders:
Description:
Exam1 MCBII
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