MICRO Lec22 LO.txt

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Author:
karennnb
ID:
13732
Filename:
MICRO Lec22 LO.txt
Updated:
2010-04-09 20:20:29
Tags:
microbiology
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Description:
lec 22 learning objectives
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  1. Antibodies are _ shaped
    Y
  2. The two parts of the antibody are __ and __
    Fab and Fc
  3. Antibody chains are held together by __ bonds
    Disulfide
  4. Antibodies have __ and __ regions
    Variable, constant
  5. Antibodies are made of __ and __ chains
    Light, heavy
  6. The Fab region is the __ part of the Y
    2 short branches
  7. the Fc region is the __ part of the Y
    base
  8. the antigen-binding site is on the __ region of antibodies
    Fab
  9. What are the 6 ways antibodies fight bacterial and viral infections
    Neutralize, inferefere, agglutinate, opsonize, activate complement, tag
  10. What are the five classes of antibodies (based on Fc part): Ig_
    M, G, A, D, E
  11. Ig_ is the first response
    M
  12. IgM Fc parts join together to form a __
    Pentanamer
  13. Ig_ is a main serum that�s the longest lived
    G
  14. Ig_ can be transported across the placenta from mom to baby
    G
  15. Ig_ is mainly secreted by mucuous membrane
    A
  16. IgA is the most abundant class formed and joins together to form __
    Dimers
  17. Ig_ is found on memory B cells
    D
  18. IgD has a very __ half life
    Short
  19. Ig_ is responsible for allergic responses
    E
  20. How do antibodies differentiate
    Antibody-producing cells undergo class switching
  21. __ is the cytokine signal that stimulates class switching
    interleukins
  22. the first immune response produces Ig_ and some Ig_
    M, G
  23. The second immune response produces mostly Ig_
    G
  24. Antibody chains are put together by __
    Combining parts
  25. A heavy chain is a combination of the _, _, and _ regions
    VDJ
  26. A light chain is combination of the _ and _ regions
    VJ
  27. B cells produce __, or B cell receptors
    Surface bound Ab
  28. If an activated helper T cell recognizes an epitope on the B cell, it will bind to the B cell and create a __
    MHC II/Antigen complex
  29. After activation, a B cell can become a __ that secretes antibodies
    Plasma cell
  30. The helper t cell secretes cytokines that cause B cell to __
    Makes clones of itself
  31. B cells that can bind Ag in the bone marrow of a fetus undergo __
    Apoptosis
  32. If a B cell presents an epitope but no helper T cells can bind to activate it, the B cells becomes __
    energic

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