05 Study Guide

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NursyDaisy
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137372
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05 Study Guide
Updated:
2012-04-30 22:54:51
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Pathophysiology
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Innate Defenses: Inflammation
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  1. Inflammation:
    a. destroys injurious agents.
    b. confines injurious agents.
    c. stimulated and enhances immunity.
    d. promotes healing.
    e. All of the above are correct.
    e. All of the above are correct.
  2. Inflammatory microcirculation changes involve all of the following except:
    A. vasodilation.
    B. days to develop.
    C. increased vascular permeability.
    D. exudation of leukocytes to injury site.
    B. days to develop.
    (this multiple choice question has been scrambled)
  3. A phagocyte's role begins with an inflammatory response. The sequence for phagocytosis is:
    A. margination, diapedesis, recognition, adherence, ingestion, fusion with lysosomes inside the phagocyte, destruction of the target.
    B. recognition of the target, margination or pavementing, destruction of the target by lysosomal enzymes.
    C. margination or pavementing, recognition of the target, adherence or binding, fusion with lysosomes inside the phagocyte.
    D. diapedesis, margination or pavementing, phagosome formation, recognition of the target, fusion with lysosomes inside the phagocyte.
    A. margination, diapedesis, recognition, adherence, ingestion, fusion with lysosomes inside the phagocyte, destruction of the target.
    (this multiple choice question has been scrambled)
  4. Chemotactic factors for phagocytes include all of the following except:
    A. mast cell degranulation products.
    B. streptolysins.
    C. plasminogen activator.
    D. prostaglandins.
    E. complement components.
    B. steptolysins.
    (this multiple choice question has been scrambled)
  5. Which is not a local manifestation of inflammation?
    A. redness
    B. pain
    C. leukocytosis
    D. heat
    E. swelling
    C. leukocytosis
    (this multiple choice question has been scrambled)
  6. Complement is:
    A. a hormone.
    B. a lymphokine.
    C. an antibody.
    D. a series of proteins in the blood.
    D. a series of proteins in the blood.
    (this multiple choice question has been scrambled)
  7. Diapedesis is a process in which:
    A. neutrophils migrate from the blood stream to an injured tissue site.
    B. phagocytes stick to capillary and venule walls.
    C. bacteria are coated with an opsonin.
    D. there is oxygen-dependent killing of cells.
    A. neutrophils migrate from the blood stream to an injured tissue site.
    (this multiple choice question has been scrambled)
  8. Interferon:
    A. interferes with the ability of bacteria to cause disease.
    B. prevents viruses from infecting healthy host cells.
    C. increases the phagocytic activity of macrophages.
    D. increases the number of circulating neutrophils.
    E. inhibits macrophage migration from inflamed sites.
    B. prevents viruses from infecting healthy host cells.
    (this multiple choice question has been scrambled)
  9. The complement system can be activated by:
    A. the binding of complement 1 to a complement-binding site of an antibody.
    B. the binding of complement 3 to bacteria.
    C. components of other plasma protein systems.
    D. Both a and c are correct.
    E. a, b, and c are correct.
    E. a, b, and c are correct. (a. the binding of complement 1 to a complement-binding site of an antibody. b. components of other plasma protein systems. c. the binding of complement 3 to bacteria.)
    (this multiple choice question has been scrambled)
  10. Which is not a systemic manifestation of inflammation?
    A. fever
    B. exudation
    C. leukocytosis
    D. increased acute-phase reactants
    B. exudation
    (this multiple choice question has been scrambled)
  11. The inflammatory response:
    A. prevents formation of abscesses.
    B. minimizes injury and promotes healing.
    C. prevents blood from entering the injured tissue.
    D. elevates body temperature to prevent spread of infection.
    B. minimizes injury and promotes healing.
    (this multiple choice question has been scrambled)
  12. Scar tissue is:
    A. fibrinogen that has entrapped phagocytes and neurons.
    B. nonfunctional collagenous and fibrotic tissue.
    C. functional tissue that follows wound healing.
    D. regenerated tissue formed in the area of injury.
    B. nonfunctional collagenous and fibrotic tissue.
    (this multiple choice question has been scrambled)
  13. Repair involves processes that:
    A. shrink the wound.
    B. Both a and b are correct.
    C. fill the wound.
    D. cover or seal the wound.
    E. a, b, and c are correct.
    E. a, b, and c are correct. (a. fill the wound. b. cover or seal the wound. c. shrink the wound.)
    (this multiple choice question has been scrambled)
  14. Swelling during acute inflammation is caused by:
    A. neutrophilic margination.
    B. collagenase.
    C. fluid and cellular exudation.
    D. lymphocytic margination.
    E. anaerobic glycolysis.
    C. fluid and cellular exudation.
    (this multiple choice question has been scrambled)
  15. Which is not released from mast cells during degranulation?
    A. complement
    B. vasoactive amines
    C. chemotactic factors
    D. histamine
    A. complement
    (this multiple choice question has been scrambled)
  16. Chronic inflammation is characterized by:
    A. neutrophilic infiltration.
    B. lymphocytic and macrophagic infiltration.
    C. metaplasia.
    D. hypertrophy.
    e. All of the above are correct.
    B. lymphocytic and macrophagic infiltration.
    (this multiple choice question has been scrambled)
  17. Which is synthesized by mast cells?
    A. serotonin
    B. leukotrienes
    C. eosinophil chemotactic factor
    D. neutrophil chemotactic factor
    E. histamine
    B. leukotrienes
    (this multiple choice question has been scrambled)
  18. Primary intention healing:
    A. requires little wound epithelialization.
    B. a, b, and c are correct.
    C. Both b and c are correct.
    D. requires little wound contraction.
    E. involves collagen synthesis.
    B. a, b, and c are correct. (a. involves collagen synthesis. b. requires little wound contraction. c. requires little wound epithelialization.)
    (this multiple choice question has been scrambled)
  19. Interleukins:
    a. provide messages between leukocytes.
    b. are produced in response to tissue injury.
    c. stimulate cells to produce antiviral substances.
    d. increase antibody production and population of T cells.
    e. All of the above are correct.
    e. All of the above are correct.
  20. Eosinophils:
    a. are agranulocytes.
    b. control the vascular effects of serotonin and histamine by lysosomal mediators.
    c. have a lysosomal protein that can dissolve the surface membranes of parasites.
    d. All of the above are correct.
    e. Both b and c are correct.
    e. Both b and c are correct. ( b. control the vascular effects of serotonin and histamine by lysosomal mediators. c. have a lysosomal protein that can dissolve the surface membranes of parasites.)
  21. Resolution
    A. increases the phagocytic activity of macrophages
    B. inhibits production of proinflammatory cytokines
    C. is avascular
    D. proliferates antigen-specific clones of B and T cells
    E. contains new capillaries, fibroblasts, and macrophages
    F. increases vascular permeability
    G. inhibit macrophage migration from the inflamed area
    H. return to original structure and physiologic function
    H. return to original structure and physiologic function
    (this multiple choice question has been scrambled)
  22. Bradykinin
    A. return to original structure and physiologic function
    B. is avascular
    C. inhibits production of proinflammatory cytokines
    D. inhibit macrophage migration from the inflamed area
    E. contains new capillaries, fibroblasts, and macrophages
    F. increases vascular permeability
    G. increases the phagocytic activity of macrophages
    H. proliferates antigen-specific clones of B and T cells
    F. increases vascular permeability
    (this multiple choice question has been scrambled)
  23. Granulation tissue
    A. return to original structure and physiologic function
    B. contains new capillaries, fibroblasts, and macrophages
    C. is avascular
    D. inhibit macrophage migration from the inflamed area
    E. increases vascular permeability
    F. increases the phagocytic activity of macrophages
    g . inhibits production of proinflammatory cytokines
    h. proliferates antigen-specific clones of B and T cells
    B. contains new capillaries, fibroblasts, and macrophages
    (this multiple choice question has been scrambled)
  24. IL-10
    A. is avascular
    B. return to original structure and physiologic function
    C. increases vascular permeability
    D. inhibit macrophage migration from the inflamed area
    E. inhibits production of proinflammatory cytokines
    F. increases the phagocytic activity of macrophages
    G. proliferates antigen-specific clones of B and T cells
    H. contains new capillaries, fibroblasts, and macrophages
    D. inhibit macrophage migration from the inflamed area
    (this multiple choice question has been scrambled)
  25. Scar
    A. inhibit macrophage migration from the inflamed area
    B. proliferates antigen-specific clones of B and T cells
    C. inhibits production of proinflammatory cytokines
    D. is avascular
    E. return to original structure and physiologic function
    F. increases the phagocytic activity of macrophages
    G. contains new capillaries, fibroblasts, and macrophages
    H. increases vascular permeability
    D. is avascular
    (this multiple choice question has been scrambled)

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