09 Study Guide

Card Set Information

Author:
NursyDaisy
ID:
137376
Filename:
09 Study Guide
Updated:
2012-04-30 22:30:31
Tags:
Pathophysiology
Folders:

Description:
Biology of Cancer and Tumor Spread
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user NursyDaisy on FreezingBlue Flashcards. What would you like to do?


  1. Neoplasia
    A. lack of cellular differentiation or specialization, primitive cells
    B. abnormal, proliferating cells possessing a higher degree of autonomy than normal cells
    C. increase in absolute number cells
    D. differentiation of dividing cells into cellular types not ordinarily found in a given area.
    E. variation in size, shape, and arrangement of cells
    F. cancer cells' independence from normal cellular controls
    B. abnormal, proliferating cells possessing a higher degree of autonomy than normal cells
    (this multiple choice question has been scrambled)
  2. Anaplasia
    A. increase in absolute number cells
    B. abnormal, proliferating cells possessing a higher degree of autonomy than normal cells
    C. cancer cells' independence from normal cellular controls
    D. variation in size, shape, and arrangement of cells
    E. lack of cellular differentiation or specialization, primitive cells
    F. differentiation of dividing cells into cellular types not ordinarily found in a given area.
    E. lack of cellular differentiation or specialization, primitive cells
    (this multiple choice question has been scrambled)
  3. Autonomy
    A. increase in absolute number cells
    B. variation in size, shape, and arrangement of cells
    C. differentiation of dividing cells into cellular types not ordinarily found in a given area.
    D. abnormal, proliferating cells possessing a higher degree of autonomy than normal cells
    E. lack of cellular differentiation or specialization, primitive cells
    F. cancer cells' independence from normal cellular controls
    F. cancer cells' independence from normal cellular controls
    (this multiple choice question has been scrambled)
  4. Which characterize(s) cancer cells?
    a. poorly differentiated
    b. metastasis
    c. infiltrative growth mode
    d. poor cellular cohesiveness
    e. All of the above are correct.
    e. All of the above are correct.
  5. Which is not a malignant tumor?
    A. rhabdomyoma
    B. glioma
    C. adenocarcinoma
    D. leukemia
    A. rhabdomyoma
    (this multiple choice question has been scrambled)
  6. Endocrine hormone secretion is increased in:
    A. tumors of having a high fatality rate.
    B. tumors having little resemblance to tissue of origin.
    C. benign tumors.
    D. nonencapsulated tumors.
    C. benign tumors.
    (this multiple choice question has been scrambled)
  7. Metastasis is:
    A. growth of benign or malignant neoplastic cells.
    B. an alteration in normal cellular growth.
    C. the ability to establish a secondary neoplasm at a new site.
    D. mutational.
    C. the ability to establish a secondary neoplasm at a new site.
    (this multiple choice question has been scrambled)
  8. Carcinoma in situ is:
    A. preinvasive.
    B. a teratoma.
    C. a glandular or epithelial lesion.
    D. a carcinoma that has broken through the basement membrane.
    E. Both a and b are correct.
    E. Both a and b are correct. (a. preinvasive. b. a glandular or epithelial lesion.)
    (this multiple choice question has been scrambled)
  9. Stage 3 or C
    A. increased extracellular proteolysis
    B. substances produced by cancer cells
    C. increased metabolite transport
    D. unmasks mutations in recessive genes
    E. "rounded-up" cells
    F. methylation of DNA shuts off genes
    G. cancer has spread to regional structures
    G. cancer has spread to regional structures
    (this multiple choice question has been scrambled)
  10. Tumor markers
    A. increased extracellular proteolysis
    B. increased metabolite transport
    C. cancer has spread to regional structures
    D. unmasks mutations in recessive genes
    E. "rounded-up" cells
    F. methylation of DNA shuts off genes
    G. substances produced by cancer cells
    G. substances produced by cancer cells
    (this multiple choice question has been scrambled)
  11. Loss of heterozygosity
    A. increased metabolite transport
    B. "rounded-up" cells
    C. unmasks mutations in recessive genes
    D. cancer has spread to regional structures
    E. methylation of DNA shuts off genes
    f . substances produced by cancer cells
    g. increased extracellular proteolysis
    C. unmasks mutations in recessive genes
    (this multiple choice question has been scrambled)
  12. Silencing
    A. cancer has spread to regional structures
    B. increased extracellular proteolysis
    C. substances produced by cancer cells
    D. unmasks mutations in recessive genes
    E. methylation of DNA shuts off genes
    F. "rounded-up" cells
    G. increased metabolite transport
    E. methylation of DNA shuts off genes
    (this multiple choice question has been scrambled)
  13. Known routes of metastasis include:
    A. Both b and c are correct.
    B. continuous extension.
    C. a, b, and c are correct.
    D. lymphatic spread.
    E. bloodstream dissemination.
    C. a, b, and c are corret. (a. continuous extension. b. lymphatic spread. c. bloodstream dissemination.)
    (this multiple choice question has been scrambled)
  14. Tumor suppressor genes are:
    A. genes that produce proteins that inhibit cellular division.
    B. genes that have the ability to transform a normal cell into a cancerous cell.
    C. Both b and c are correct.
    D. normal genes that regulate growth and development.
    A. genes that produce proteins that inhibit cellular division.
    (this multiple choice question has been scrambled)
  15. In the current theory of carcinogenesis:
    A. Both b and d are correct.
    B. several mutagenic "hits" are required.
    C. sequential genetic changes occur.
    D. the sequence is initiation-promotion-progression.
    E. mutations in somatic cells are transmitted to future generations.
    A. Both b and d are correct. (b. several mutagenic "hits" are required. d. sequential genetic changes occur.)
    (this multiple choice question has been scrambled)
  16. Which is not involved in metastasis?
    A. interference
    B. initial establishment
    C. dissemination
    D. invasion
    E. proliferation
    A. interference
    (this multiple choice question has been scrambled)
  17. Oncogenic viruses are:
    a. DNA viruses.
    b. RNA viruses.
    c. capable of incorporation into host genes.
    d. capable of transforming a normal cell into a cancerous cell.
    e. All of the above are correct.
    e. All of the above are correct.
  18. The p53 gene:
    a. enables cells to cope with DNA damage.
    b. blocks the proliferation of cells that have suffered carcinogenic mutations.
    c. mutations are the most common genetic lesion in human cancer.
    d. mutations disable an emergency brake on cell proliferation.
    e. All of the above are correct.
    e. All of the above are correct.
  19. Local invasive factors include all except:
    A. lytic enzymes.
    B. cellular multiplication.
    C. increased cellular adhesion.
    D. mechanical pressure.
    C. increased cellular adhesion.
    (this multiple choice question has been scrambled)
  20. The sequence of carcinogenesis is:
    A. ionizing radiation, caretaker gene activity, and point mutations.
    B. carcinoma in situ, altered genetic molecules, and sequential mutagenic changes.
    C. exposure to carcinogens, selection of subclones, and mutation of genetic molecules.
    D. viral infection, several mutagenic "hits" to DNA.
    D. viral infection, several mutagenic "hits" to DNA.
    (this multiple choice question has been scrambled)
  21. An adenoma is:
    A. a teratoma.
    B. a glandular epithelial neoplasm.
    C. Both a and b are correct.
    D. benign.
    E. a malignant epithelial tumor.
    C. Both a and b are correct. (a. benign. b. a glandular epithelial neoplasm.)
    (this multiple choice question has been scrambled)
  22. AFP
    A. Wilms tumor
    B. prostate gland
    C. multiple myeloma
    D. GI, pancreas
    E. retinoblastomas
    F. hepatic, germ cells
    F. hepatic, germ cells
    (this multiple choice question has been scrambled)
  23. CEA
    A. hepatic, germ cells
    B. Wilms tumor
    C. GI, pancreas
    D. prostate gland
    E. retinoblastomas
    F. multiple myeloma
    C. GI, pancreas
    (this multiple choice question has been scrambled)
  24. Urinary Bence-Jones protein
    A. prostate gland
    B. GI, pancreas
    C. Wilms tumor
    D. hepatic, germ cells
    E. retinoblastomas
    F. multiple myeloma
    F. multiple myeloma
    (this multiple choice question has been scrambled)
  25. PSA
    A. GI, pancreas
    B. retinoblastomas
    C. multiple myeloma
    D. hepatic, germ cells
    E. prostate gland
    F. Wilms tumor
    E. prostate gland
    (this multiple choice question has been scrambled)

What would you like to do?

Home > Flashcards > Print Preview