09 Study Guide

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  1. Neoplasia
    A. differentiation of dividing cells into cellular types not ordinarily found in a given area.
    B. lack of cellular differentiation or specialization, primitive cells
    C. variation in size, shape, and arrangement of cells
    D. cancer cells' independence from normal cellular controls
    E. abnormal, proliferating cells possessing a higher degree of autonomy than normal cells
    F. increase in absolute number cells
    E. abnormal, proliferating cells possessing a higher degree of autonomy than normal cells
    (this multiple choice question has been scrambled)
  2. Anaplasia
    A. differentiation of dividing cells into cellular types not ordinarily found in a given area.
    B. lack of cellular differentiation or specialization, primitive cells
    C. variation in size, shape, and arrangement of cells
    D. abnormal, proliferating cells possessing a higher degree of autonomy than normal cells
    E. increase in absolute number cells
    F. cancer cells' independence from normal cellular controls
    B. lack of cellular differentiation or specialization, primitive cells
    (this multiple choice question has been scrambled)
  3. Autonomy
    A. abnormal, proliferating cells possessing a higher degree of autonomy than normal cells
    B. lack of cellular differentiation or specialization, primitive cells
    C. differentiation of dividing cells into cellular types not ordinarily found in a given area.
    D. increase in absolute number cells
    E. cancer cells' independence from normal cellular controls
    F. variation in size, shape, and arrangement of cells
    E. cancer cells' independence from normal cellular controls
    (this multiple choice question has been scrambled)
  4. Which characterize(s) cancer cells?
    a. poorly differentiated
    b. metastasis
    c. infiltrative growth mode
    d. poor cellular cohesiveness
    e. All of the above are correct.
    e. All of the above are correct.
  5. Which is not a malignant tumor?
    A. leukemia
    B. rhabdomyoma
    C. glioma
    D. adenocarcinoma
    B. rhabdomyoma
    (this multiple choice question has been scrambled)
  6. Endocrine hormone secretion is increased in:
    A. benign tumors.
    B. tumors having little resemblance to tissue of origin.
    C. nonencapsulated tumors.
    D. tumors of having a high fatality rate.
    A. benign tumors.
    (this multiple choice question has been scrambled)
  7. Metastasis is:
    A. the ability to establish a secondary neoplasm at a new site.
    B. mutational.
    C. growth of benign or malignant neoplastic cells.
    D. an alteration in normal cellular growth.
    A. the ability to establish a secondary neoplasm at a new site.
    (this multiple choice question has been scrambled)
  8. Carcinoma in situ is:
    A. preinvasive.
    B. a carcinoma that has broken through the basement membrane.
    C. a glandular or epithelial lesion.
    D. a teratoma.
    E. Both a and b are correct.
    E. Both a and b are correct. (a. preinvasive. b. a glandular or epithelial lesion.)
    (this multiple choice question has been scrambled)
  9. Stage 3 or C
    A. unmasks mutations in recessive genes
    B. substances produced by cancer cells
    C. increased extracellular proteolysis
    D. increased metabolite transport
    E. methylation of DNA shuts off genes
    F. cancer has spread to regional structures
    G. "rounded-up" cells
    F. cancer has spread to regional structures
    (this multiple choice question has been scrambled)
  10. Tumor markers
    A. increased metabolite transport
    B. methylation of DNA shuts off genes
    C. unmasks mutations in recessive genes
    D. "rounded-up" cells
    E. cancer has spread to regional structures
    F. increased extracellular proteolysis
    G. substances produced by cancer cells
    G. substances produced by cancer cells
    (this multiple choice question has been scrambled)
  11. Loss of heterozygosity
    A. "rounded-up" cells
    B. unmasks mutations in recessive genes
    C. cancer has spread to regional structures
    D. increased metabolite transport
    E. methylation of DNA shuts off genes
    f . substances produced by cancer cells
    g. increased extracellular proteolysis
    B. unmasks mutations in recessive genes
    (this multiple choice question has been scrambled)
  12. Silencing
    A. substances produced by cancer cells
    B. "rounded-up" cells
    C. increased metabolite transport
    D. increased extracellular proteolysis
    E. methylation of DNA shuts off genes
    F. unmasks mutations in recessive genes
    G. cancer has spread to regional structures
    E. methylation of DNA shuts off genes
    (this multiple choice question has been scrambled)
  13. Known routes of metastasis include:
    A. a, b, and c are correct.
    B. Both b and c are correct.
    C. lymphatic spread.
    D. continuous extension.
    E. bloodstream dissemination.
    A. a, b, and c are corret. (a. continuous extension. b. lymphatic spread. c. bloodstream dissemination.)
    (this multiple choice question has been scrambled)
  14. Tumor suppressor genes are:
    A. Both b and c are correct.
    B. normal genes that regulate growth and development.
    C. genes that produce proteins that inhibit cellular division.
    D. genes that have the ability to transform a normal cell into a cancerous cell.
    C. genes that produce proteins that inhibit cellular division.
    (this multiple choice question has been scrambled)
  15. In the current theory of carcinogenesis:
    A. the sequence is initiation-promotion-progression.
    B. sequential genetic changes occur.
    C. Both b and d are correct.
    D. mutations in somatic cells are transmitted to future generations.
    E. several mutagenic "hits" are required.
    C. Both b and d are correct. (b. several mutagenic "hits" are required. d. sequential genetic changes occur.)
    (this multiple choice question has been scrambled)
  16. Which is not involved in metastasis?
    A. proliferation
    B. invasion
    C. dissemination
    D. interference
    E. initial establishment
    D. interference
    (this multiple choice question has been scrambled)
  17. Oncogenic viruses are:
    a. DNA viruses.
    b. RNA viruses.
    c. capable of incorporation into host genes.
    d. capable of transforming a normal cell into a cancerous cell.
    e. All of the above are correct.
    e. All of the above are correct.
  18. The p53 gene:
    a. enables cells to cope with DNA damage.
    b. blocks the proliferation of cells that have suffered carcinogenic mutations.
    c. mutations are the most common genetic lesion in human cancer.
    d. mutations disable an emergency brake on cell proliferation.
    e. All of the above are correct.
    e. All of the above are correct.
  19. Local invasive factors include all except:
    A. increased cellular adhesion.
    B. mechanical pressure.
    C. lytic enzymes.
    D. cellular multiplication.
    A. increased cellular adhesion.
    (this multiple choice question has been scrambled)
  20. The sequence of carcinogenesis is:
    A. ionizing radiation, caretaker gene activity, and point mutations.
    B. exposure to carcinogens, selection of subclones, and mutation of genetic molecules.
    C. viral infection, several mutagenic "hits" to DNA.
    D. carcinoma in situ, altered genetic molecules, and sequential mutagenic changes.
    C. viral infection, several mutagenic "hits" to DNA.
    (this multiple choice question has been scrambled)
  21. An adenoma is:
    A. a teratoma.
    B. a glandular epithelial neoplasm.
    C. Both a and b are correct.
    D. benign.
    E. a malignant epithelial tumor.
    C. Both a and b are correct. (a. benign. b. a glandular epithelial neoplasm.)
    (this multiple choice question has been scrambled)
  22. AFP
    A. multiple myeloma
    B. Wilms tumor
    C. retinoblastomas
    D. hepatic, germ cells
    E. GI, pancreas
    F. prostate gland
    D. hepatic, germ cells
    (this multiple choice question has been scrambled)
  23. CEA
    A. hepatic, germ cells
    B. prostate gland
    C. multiple myeloma
    D. Wilms tumor
    E. retinoblastomas
    F. GI, pancreas
    F. GI, pancreas
    (this multiple choice question has been scrambled)
  24. Urinary Bence-Jones protein
    A. multiple myeloma
    B. GI, pancreas
    C. hepatic, germ cells
    D. prostate gland
    E. Wilms tumor
    F. retinoblastomas
    A. multiple myeloma
    (this multiple choice question has been scrambled)
  25. PSA
    A. hepatic, germ cells
    B. multiple myeloma
    C. GI, pancreas
    D. Wilms tumor
    E. prostate gland
    F. retinoblastomas
    E. prostate gland
    (this multiple choice question has been scrambled)
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137376
Card Set
09 Study Guide
Description
Biology of Cancer and Tumor Spread
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