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Xanthine Bronchodilator that sometimes is effective in cases where Sympathomimetics have not been effective.
Mechanism of Action
Relaxes bronchial smooth muscle but does not act on adrenergic receptors. Mild diuretic properties can increase HR & Cardiac output.
Onset of Action
- Onset: 15min
- Peak: 15min
- Duration: Varies
- Half-life: 4hrs
Treatment of infants w/ apnea. Bronchial asthma, Reversible bronchospasm associated w/ chronic Bronchitis, Emphysema, CHF and Pulmonary Edema
Known Hypersensitivity, Uncontrolled Cardiac Arrhythmias
Cardiac monitor, Arrhythmia, PVC, Tachycardia, palpitation, chest pain, nervousness, headache, seizure, nausea/vomiting, hypotension from rapid administration.
CHF/fluid overload NOT present 250 or 500mg (2-5mg/kg) in 90 or 80ml of 5% Dextrose infused over 20-30min
CHF Present 250 or 500mg in 20ml of 5% Dextrose
6mg/kg loading dose infused over 20-30min
- Adult: Titrate to Effect
- Pedi: Don't exceed 12mg/kg in 24hrs
Route of Administration
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