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Description
Serotonin Antagonist
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Mechanism of Action
Blocks serotonin receptors in the CTZ, stomach and small intestine.
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Onset of Action
- Onset: 10-30 min
- Peak: 1.5 hrs
- Duration: 8 hrs
- Half-life: 3 hrs
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Indications
nausea, vomiting
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Contraindications
Known Hypersensitivity
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Precautions/ Side Effects
- Patients taking other serotonin blockers
- Rifampin reduces effects
- Headache
- light headedness
- dizziness
- tiredness
- constipation
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Route of Administration
IV, PO, IM (last resort)
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How Supplied
Vials, 4mg and 8mg tablets
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