Ondansetron (Zofran)

Card Set Information

Author:
Kgren
ID:
138045
Filename:
Ondansetron (Zofran)
Updated:
2012-03-02 10:04:00
Tags:
Paramedic Drugs
Folders:

Description:
Ondansetron (Zofran)
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  1. Class
    Antiemetic
  2. Description
    Serotonin Antagonist
  3. Mechanism of Action
    Blocks serotonin receptors in the CTZ, stomach and small intestine.
  4. Onset of Action
    • Onset: 10-30 min
    • Peak: 1.5 hrs
    • Duration: 8 hrs
    • Half-life: 3 hrs
  5. Indications
    nausea, vomiting
  6. Contraindications
    Known Hypersensitivity
  7. Precautions/ Side Effects
    • Patients taking other serotonin blockers
    • Rifampin reduces effects
    • Headache
    • light headedness
    • dizziness
    • tiredness
    • constipation
  8. Adult Dose
    4-8mg
  9. Pedi Dose
    0.15mg/kg
  10. Max Dose
    NONE
  11. Route of Administration
    IV, PO, IM (last resort)
  12. How Supplied
    Vials, 4mg and 8mg tablets

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