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What are the inhalantion anesthetics characteristics?
- Minimal toxicity to patient-cardiovascular, repiratory, hepatic, renal, and nervous system
- Minimal toxicity to operating room personnel
- Ease of administration
- Rapid and gentle induction and recovery
- Depth of anesthesia easily controlled and altered
- Good muscle relaxation
- Adequate postoperative analgesia
- Low cost
- Adequate potency to achieve surgical anesthesia
- Nonflammable and nonexplosive
- Doesn't require expensive equipment
Define vapor pressure
The measure of the amount of liquid anesthetic that will evaporate at 200F (680F)
How do you know what liquid anestheti evaporate faster?
The way you know is by the number of mmHg the higher it is the more is going to vaporize.
Which two liquid anesthetics have almost the same amount of pressure?
Which inhalent anesthetic can be used in a nonprecision or wick vaporizer?
Why is the use of precision vaporizer use?
Because it limits the evaporation of these agents and allows for their safe use.
Why can methoxyflurane be used in a nonprecision vaporizer?
Because its maximum concentration is 3.5-4% and Isoflurane and halothane maximum concentration is of 5%
T or F. Each type of vaporizer can be used with any specific agent and vapor pressure
False: Each type of vaporizer is designed for a specific agent and its vapor pressure
What is solubility coeffiecient?
A measure of the distribution of the inhalation agent between the blood and gas phases in the body.
Agents with high or low solubility coeffiecient cause slower anesthetic induction and recovery and slower change of depth of anesthesia and allows for rapid absorption into tissue (the sponge effect)?
Agents with low solubility coefficients are extremely soluble into blood and tissue.
Solubility coefficients of various anesthetic agents
- 1. Desflurane-0.42%
- 2. Nitrous Oxide-0.5%
- 3. Sevoflurane-0.68%
- 4. Isoflurane-1.4%
- 5. Halothane-2.4%
- 6. Methoxyflurane-13.0%
Minimum alveolar concentration (MAC)
Defined as the minimum alveolar concentration of an anesthetic at 1 atmosphere (760 mm Hg) that produces immobility in 50% of subjects exposed to a noxious stimulus.
Refers to the quantity of an inhalant anesthetic must be administered to cause a desired effect.
True or False. The lower the mac value the more potent the anesthetic agent.
When in surigical plane of anesthesia by what do you multiply MAC?
- 1. Methoxyflurane-0.23% in dog, 0.16% in cat
- 2. Halothane-0.8% in dog, 0.8 –1.2 % in cat
- 3. Isoflurane-1.2% in dog, 1.2-1.6% in cat
- 4. Sevoflurane-2.3% in dog, 2.6% in cat
- 5. Desflurane-7.2%
- 6. Nitrous Oxide-188%