biochem RLS

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Author:
embryo
ID:
139893
Filename:
biochem RLS
Updated:
2012-03-05 21:40:01
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biochem RLS
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Description:
MS1 biochem RLS
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  1. glycolysis
    PFK-1: fructose-6-phosphate->fructose-1,6-bisphosphate
  2. gluconeogenesis
    Fructose-1,6-bisphosphatase: frutctose-1,6-bisphosphate-> fructose-6-phosphate
  3. TCA cycle
    isocitrate dehydrogenase: isocitrate->alpha ketoglutarate
  4. glycogen synthesis
    glycogen synthase
  5. glycogenolysis
    glycogen phosphorylase
  6. HMP shunt
    glucose-6-phosphate dehydrogenase: G6P->6-phosphogluconolactone
  7. de novo pyrimidine synthesis
    carbamoyl phosphate synthetase 2
  8. de novo purine synthesis
    glutamine-PRPP-amidotransferase
  9. urea cycle
    carbamoyl phosphate synthetase 1
  10. FA synthesis
    Acetyl-CoA carboxylase
  11. FA oxidation
    carnitine acyltransferase 1
  12. ketogenesis
    HMG-CoA synthesis
  13. cholesterol synthesis
    HMG-CoA reductase
  14. Requires biotin
    • acetyl CoA-> malonyl CoA
    • pyruvate carboxylase: pyruvate->OAA
    • propionyl CoA-methylmalonyl CoA
  15. Requires thiamine (TPP)
    • transketolase: R5P->F6P
    • pyruvate dehydrogenase: pyruvate ->acetyl CoA
    • alpha ketoglutarate dehydrogenase: alpha ketoglutarate->succinyl CoA

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