Neonates Chapter 8

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docmc90
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140209
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Neonates Chapter 8
Updated:
2012-03-07 01:46:26
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Pharmacology neonates
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Pharmacology in Neonate
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  1. Drug transfer across the placenta is affected by which of the following?
    a. Concentration difference
    b. Lipid solubility of the drug
    c. Degree of ionization
    d. Diffusion Coefficient
    e. Molecular drug weight
    A, B, C and E
  2. Teratogenic drugs generally have their greatest effect during:
    The first trimester
  3. A lipid-soluble drug has which of the following characteristics?
    a. Readily cross cell membranes
    b. Concentration is higher in tissues than in plasma
    c. High affinity for protein binding
    d. 10% is bound to albumin
    e. Distributed slowly to the heart and kidneys
    A and C
  4. Of the following, which is not a type of biochemical reaction of drug metabolism in the liver?
    Excretion (p. 226)
  5. Of the following antibiotics, which is considered to be bacteriostatic?
    Tetracycline (p. 231)
  6. Name a Penicillin
    Ampicillin
  7. Name a cephalosporins
    Cephalexin
  8. Name a Aminoglycosides
    Gentamicin
  9. Name a Macrolide
    Erythromycin
  10. Name a Quinolone
    Enoxacin
  11. Name a Tetracycline
    Doxycycline
  12. Name a sulfonamide
    Sulfadiazine
  13. Name a Antifungal
    nystain
  14. Name an antiviral
    Ribavirin
  15. Which drug would be most appropriate to treat congestive heart failure?
    Digoxin
  16. Which drug would be most appropriate to treat supraventricular tachycardia?
    Adenosine
  17. Which drug would be most appropriate to treat severe hypotension?
    Dopamine
  18. Acute bronchospasm would best be treated with which of the following drugs?
    Albuterol
  19. Neonatal apnea is treated with which of the following?
    Caffeine
  20. Which of the following best describes the effects of glucocorticoids?
    a. Combat infections
    b. Stabilize cell membranes
    c. Inhibit macrophage accumulation
    d. Increase the release of adrenocorticotropic hormone
    e. Promote Gluconeogenesis
    B, C, and E
  21. The drug that inhibits mast cell degranulation is:
    Cromolyn sodium
  22. Which of the following would be the drug of choice in sedating a neonate following surgery?
    Chloral hydrate (p. 252)
  23. Restlessness, irritability, tremors, high-pitched cry, and vomiting are all signs of:
    Fetal Drug withdraw

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