Pharm&Tox-CNS

Card Set Information

Author:
jenafer
ID:
140522
Filename:
Pharm&Tox-CNS
Updated:
2012-03-13 13:49:33
Tags:
DRUGS nervous nerves
Folders:

Description:
cns
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user jenafer on FreezingBlue Flashcards. What would you like to do?


  1. how the drug physiologically and/or biochemically effects the body is known as ...
    Pharmacodynamics
  2. how the drug is disposed or cleared by the body is known as ...
    Pharmacokinetics
  3. PD or PK?
    ... leads us to choose drugs that produce the desired main effects and avoid the most negative side effects for the patients.
    PD
  4. PD or PK?
    ... leads us to conside the processing of the dose andhow patient can rid itself of the drug and return to the resting state. This may be desired or wanted to be delayed.
    PK
  5. The nervous system is primarily under control of the ...
    hypothalamus (mostly) and the pituitary (partly)
  6. 3 functions of the nervous system. list in consecutive order.
    • 1- sensory
    • 2- integrative
    • 3- motor
  7. what is the importance of the nervous system? (4)
    • 1- it is the primary communication and control center
    • 2- functions in concert with endocrine system
    • 3- allows adaptation to the environment
    • 4- maintains homeostasis
  8. In the nervous system, messages or impulses are propagated via ...
    nerve fibers
  9. ... is an electronically excitable cell.
    neuron
  10. what signal type(s) does a neuron use to propagate a signal?
    electrical AND chemical signals
  11. ... are specialized connections from one neuron to others.
    synapses
  12. Which part of the neuron initially carries impulses toward the nerve cell?
    dendrites
  13. which part of the neruon carries the impulse away from the nerve cell?
    axons
  14. a nerve fiber that has a membrane that is positive charge on the outside and a negative inside charge is known as a ...
    polarized or "resting" fiber
  15. The reduction of a membranes resting potential so that it becomes less negative is known as ...
    depolarization
  16. state at which the membrane charges return to their original states is known as ...
    repolarization
  17. a neurons axon will terminate at a large number of ...
    axon terminals or TELODENDRA
  18. Which part of a Telodendra will pass to nerve impulse to its adjacent structure?
    synaptic end bulbs
  19. nerve impulses allow neurotransmitters to emit into ...
    synapses
  20. The adrenal gland produces the neurotransmitter ...
    epinephrine
  21. british name for epinephrine is ...
    adrenaline
  22. Structures of the Nervous system (4)
    • 1- brain
    • 2- spinal cord
    • 3- peripheral ganglia
    • 4- nerve fibers
  23. ions move through ... Channels
    Voltage gated channels
  24. The ... Is responsible for repolarizing the cell membrane
    Na-K-ATP pump
  25. Name 5 neurotransmitters
    • 1- acetylcholine
    • 2- norepinephrine
    • 3- dopamine
    • 4- serotonin
    • 5- GABA
  26. when pre-synaptic axon recollect neurotransmitter for the next signal
    synaptic reuptake
  27. the nervous system dividend that includes the brain and spinal cord
    CNS
  28. the nervous system divident that includes the bran and spinal cord
    PNS
  29. ... connects the CNS with endocrine glands, muscles through neurtoransmitters and receptors
    The PNS
  30. Nerve cells that carry impulses from receptors in the periphery to the CNS
    afferent nerve cells
  31. Nerve cells that carry impulses from the CNS to the receptors on muscles and glands
    Efferent nerve cells
  32. Voluntary or skeletal muscle control is controlled by the ... system
    somatic nervous system
  33. The ... system carries impulses from the CNS to the skeletal muscle
    Somatic Nervous System
  34. involuntary and unconscious muscle control is controlled by the ... system
    autonomic nervous system
  35. ... carries impulses from the CNS to cardiac muscle, smooth muscle and glands
    autonomic nervous system
  36. part of autonomic NS that is associated with "rest and digest"
    parasympathetic system
  37. part of autonomic system associated with "fight or flight"
    sympathetic system
  38. The parasympathetic system uses ... receptors
    cholinergic
  39. They sympathetic system uses ... receptors
    adrenergic
  40. drugs that block Acetylcholine receptors are ...
    anticholinergic
  41. anticholinergics are also known as ...
    parasympatholytic
  42. stimulation causes activation of cholinergic effects. This is also known as
    parasympathomimetic
  43. neurotransmitter Acetylcholine stimulates Acetylcholine receptors, which inturn stimulate which receptors? (2)
    • 1- Nicotinic receptors
    • 2- Muscarinic receptors
  44. The neurotransmitter ... works on both Alpha receptors
    Epinephrine and Norepinephrine
  45. which enzyme on acetylcholine triggers its degradation into choline and acetyl coenzyme A, thus terminating its effect.
    acetylcholinesterase
  46. receptors which can be classified as a subtype of adrenergic receptor, their activation triggers a complex range of autonomic responses.
    Alpha receptors
  47. condition of having dilated pupils
    mydriasis
  48. two subtypes of Alpha-1 receptors
    • 1- Alpha-1 Agonists
    • 2- Alpha-2 Blockers
  49. Which Alpha receptor is not intentionally used in Veterinary Medicine?
    Alpha-1 Agonists
  50. Alpha receptor for vasocontriction
    Alpha-1 agonists
  51. Alpha receptor for vasodilation
    Alpha-1 blockers
  52. drug used for vasodilation
    acepromazine
  53. Alpha receptor for sedation and analgesia
    Alpha-2 agonists
  54. Two types of Alpha-2 subtype receptors
    • 1- Alpha-2 agonists
    • 2- Alpha-2 antagonists
  55. Name two drugs that we use as a Alpha-2 antagonists
    • 1- yohimbine
    • 2- atipamazole
  56. which neurotransmitter works on both alpha receptors
    epinephrine and norepinephrine
  57. G-protein couples receptors
    Beta receptors
  58. which receptor activates a Gs proteins
    beta receptors
  59. increased ... activates protein kinase A, which phosphorylates cellular proteins.
    cAMP or Cyclic Adenosine Monophosphate
  60. drug used for sedation and analgesia
    dexmeditomidine
  61. increased activates protein kinase A, which phosphorylates cellular proteins.
    cAMP or Cyclic Adenosine Monophosphate
  62. important receptors for signal transduction
    Beta-1 receptor
  63. receptors found [to increase functionality] in the heart and renal juxtaglomerular cells
    Beta-1 receptors
  64. receptors found in [to relax] bronchial smooth muscle and uterine muscle
    Beta-2 receptors
  65. Name 3 Beta-2 receptor inhalant drugs
    • 1- Albuterol
    • 2- Levoalbuterol
    • 3- Terbutaline (orally)
  66. contracts uterine muscles and early labor
    Terbutaline (orally)
  67. cholinergic agents are also known as ...
    parasympathomimetic
  68. promotes gastric emptying and thus controlling vomit
    metoclopramide
  69. used to diagnose myasthenia gravis or reverse neuromuscular blockade
    Edrophonium
  70. reverse neuromuscular blockade or treat urinary retention
    neostigmine
  71. used to treat myasthenia gravis but may cause heart block, bradycardia, hypotension, and increase respiratory secretions.
    pyridostygmine
  72. agent that treats sinus bradycardia (heart block)
    Anticholinergic
  73. an anticholinergic agent used in the ER/premed? (2)
    • 1- Atropine
    • 2- Glycopyrrolate
  74. older anticholinergic used for motion sickness
    Scopalamine
  75. antidote for organophosphate intoxication
    Pralidoxime
  76. Adrenergic agents are also called ...
    Catecholamines
  77. an agent that can be used to stimulate the heart
    Catecholamines
  78. agent used for treating congestive heart failure
    catecholamines
  79. Adrenergic Agents (9)
    • 1- Epinephrine and Norepinephrine
    • 2- Isoproterenol
    • 3- Phenylephrine
    • 4- Dopamine
    • 5- Phenylpropanolamine
    • 6- Dobutamine
    • 7- Ephedrine
    • 8- Terbutaline
    • 9- Albuterol/levoalbuterol
  80. name a nasal vasoconstrictor and treatment for a hypotension
    Phenylephrine
  81. Precursor of epinephrine and norepinephrine
    Dopamine
  82. agent in which an overdose may cause shock, heart failure, and increase remal perfusion
    Dopamine
  83. agent that may treat urinary incontinence in female dogs
    Phenylpropanolamine
  84. short term treatment of hypotension, heart failure
    Dobutamine
  85. agent used to treat short term treatment of hypotension and heart failure
    Dobutamine
  86. Three agents used as a bronchodilator
    • 1- Ephedrine
    • 2- Terbutaline
    • 3- Albuterol/Levoalbuterol
  87. Which receptors effect the strength of the heart contraction by increasing AV Node conduction velocity and renin release by the renal juxtaglomerular cells?
    Beta-1 Receptors exist for which organs and have what effect?
  88. Which receptors cause the bronchial smooth muscle to dialate and the Uterine muscles to relax?
    Beta-2 receptors exist for which organs and have what effect?

What would you like to do?

Home > Flashcards > Print Preview