Antitubercular Agents-End

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The flashcards below were created by user Anonymous on FreezingBlue Flashcards.


  1. Tuberculosis
    • slow growth
    • long treatment time (6-9 months)
  2. First Line Anti-Tuberculosis drugs
  3. Isoniazid
    • ethambutol
    • rifampin
    • Pyrazinamide (cidal)
  4. Second-Line Tuberculosis Agents
    • cycloserine
    • Kanamycin
    • capreomycin
    • ethionamide
    • p-aminosalicylic acid
  5. Isoniazid***
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    • Ethambutol
    • Only active against dividing mycobacteria
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    • Pyrazinamide
    • short term therapy
    • hepatotoxicity
    • used only in combination therapy
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    • P-Aminosalicylic Acid
    • increases the level of free isoniazid
  9. Rifamycins
    • active against G+ and M. Tuberculosis
    • Some G- and viruses
    • Inhibitors of DNA directed RNA polymerase
    • Bacteriocidal
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    • Rifampin
    • most active agent for treatment of Tuberculosis
    • Used only in combo
    • Inducer of hepatic P450 Oxygenases
    • Increases effects of aids medications
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    • Cycloserine
    • prevents synthesis of cross-linking peptide in formation of bacterial cell walls
  12. Anthelmintics
    drugs that have the capability to rid the body of parasitic worms or helminths
  13. Piperazine***
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    • Neurotoxic Anti-Helmintics
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    • Thiabendazole
    • Inhibits fumarate reductase
  15. Mebendazole
    blocks glucose uptake
  16. Ivermectin
    treatment of "river blindness"
  17. Benzylbenzoate***
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    • Lice treatment

Card Set Information

Author:
Anonymous
ID:
14087
Filename:
Antitubercular Agents-End
Updated:
2010-04-12 18:57:40
Tags:
Medchem
Folders:

Description:
medchem
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