Card Set Information
Which plant is morphine from?
Which is the major analgesic opiod receptor?
Which drug is a full agonist at the (mu)-opioid
Which drug is a full antagonist at the (mu)-opioid
What are the 3 major classes of opiod receptors?
mu, delta, kappa
What are some of the effects on the CNS by mu-agonist opioids?
analgesia, euphoria, sedation, respiratory depression, N/V constipation
Define tolerance of a drug.
loss of effectiveness
Define physical dependence of a drug.
Characteristic withdrawal or abstinence syndrome when
a drug is stopped or an antagonist is administered
Are opioid analgesics good for treating chronic pain?
No, but very effective for acute.
What can opioid agonists do to the GI system? eyes? MSK? heart? kidneys?
: slow GI transit, N/V
: miosis (constriction)
: truncal rigidity (which decreases respiration)
: bradycardia, hypotension in times of stress
: decreased, from lower renal flow
What can opioids do to the uterus?
What's the best way to administer an opioid med?
fixed-interval administration (ie, a regular
dose at a scheduled time)
What's the brand name of morphine?
What's the brand name of oxycodone?
IV morphine is effective for what lung condition?
dyspnea from pulmonary edema associated with left ventricular heart failure
Which narcotic is reported to have the most pronounced anti-shivering properties?
(though all opioid agonists have some propensity to reduce shivering)
What has been the most successful opioid in transdermal
What is the brand name for Naloxone?
What are some withdrawl symptoms from opioids?
rhinorrhea, lacrimation, yawning, chills, gooseflesh (piloerection), hyperventilation, hyperthermia, mydriasis,
muscular aches, vomiting, diarrhea, anxiety, and hostility
What drug is used to treat coma from opioid overdose?
What are 3 strong agonists (generic name)? ( in order of strength.
Hydromorphone, oxymorphone, Morphine
What are 3 strong agonists (brand name)?
Dilaudid (4x PO equiv. Dose), Opana (3x equiv PO dose), MSContin
What is the brand name of hydromorphone?
What is the brand name of oxymorphone?
Which opioid is used to relieve difficult-to-treat pain (neuropathic, cancer pain), especially w/ failure of morphine?
Which opioid can have a negative inotropic action on the heart
Codeine,oxycodone, dihydrocodeine, and hydrocodone --> strong agonists, partial agonists or antagonists?
Full agonists but weaker than morphine and its derivatives.
What is the generic name of Ultram?
When IV Narcan is given, how fast does it reverse the opioid effects?
Norco is combo of which 2 drugs?
hydrocodone and acetaminophen
Percocet is a combo of which 2 drugs?
oxycodone and acetaminophen
Darvocet is a combo of which 2 drugs?
Propoxyphene and acetaminophen (no longer on market)
Vicodin is a combo of which 2 drugs?
hydrocodone and acetaminophen
Name 3 drugs with hydrocodone and acetaminophen? Rank them in terms of amount of acetaminophen.
Lortab, Norco and Vicodin.
: 5/325, 7.5/325, 10/325
: 5/500, 7.5/500, 10/500
: 5/500, 7.5/750, 10/660
How many mg of codeine does Tylenol #2 have?
How many mg of codeine does Tylenol #3 have?
How many mg of codeine does Tylenol #4 have?
Which drugs are used for dull, poorly localized (visceral pain?)
Morphine and its derivatives.
Which drugs are used for somatic pain?
Codeine and its derivatives.
What's the brand name for Meperidine?
What's the connection between narcotics and histamine?
They can cause histamine release.
What's the dosing for morphine?
10 mg/ 70 kg weight
What's the brand name for Methadone?
Who should Fentanyl only be used for?
Opiod tolerant patients only. (min 1 wk of use at 25 mcg/ hr patch)
How long can meperidine be used for?
Only acutely. 48 hrs