Card Set Information
Name the 2 classes of CCBs. Which one bigger effect n heart?
Dihydropyridines--> don't affect heart much, safer S/P heart failure or in bradycardia.
Non-dihydropyramidines.--> negative chronotrope and ionotrope. Good for reducing tachycardia.
What are some drugs CCBs increases the serum level of? What food item can elevate certain dihydropyramidine concentrations?
Statins and carbamazepine (Tegretol). Grapefruit juice can interact.Allow 2 hrs before and 4 hours after consumption of pills.
Which bp meds are associated w/ sexual dysfct?
Not so much ACEI or CCB
Which class is often standard tx for diabetics?
ACEI, ARBs or non-dihydropyradine CCBs because of possible renal-protective effects (definitely for non-diabetic nephropathy)
What is Cardizem?
What is Lotensin?
What is Vasotec?
What is Accupril?
What is Altace?
What is Avapro?
What is Cozaar?
What is Micardis?
What is Benicar?
What is Dio
What is Catapres?
What is Coreg?
What is Lopressor?
What is Bystolic?
What is Inderal?
What is Norvasc?
What is Plendil?
What is Adalat or Procardia?
When should you dose diuretics?
In morning to prevent nocturnal diuresis
Which diuretic has better anti-hypertensive effects?
Thiazides > loop
What effect does thiazides have on K+, Mg, Ca, and uric acid?
Hypokalemia, hypomagnesemia, hypercalcemia,
Hyperuricemia. Also hyperlipidemia and hyperglycemia
What effect does loop diuretics have on K+, Mg, Ca, and uric acid?
Hypokalemia, hypomagnesemia, hypocalcemia,
Which 2 classes of diuretics should be avoided in CKD or DM pts?
K+sparing and aldosterone antagonists.
Name 2 aldosterone antagonists
Spirpnolactone (aldactone), , eplerenone
What's the most common loop diuretic?
Name 2 K+ sparing diuretics
Which class of diuretics are used with thiazides diuretics?
K+ sparing (they're weak diuretics with minor antihypertensive effects)
Are carbonic anhydrase inhibitors used for HTN or heart failure?
No, weakest of all diuretics, used for glaucoma
What's a side effect that up to 10% of patients have with Spironolactone?
Which diuretics contain sulfa?
All thiazides and loops and carbonic anhydrase inhibitors but studies show low chance of cross reactivity with sulfa allergy.
What's 1st line bp class for DM? CKD? Post-MI? LVH?
DM and CKD
: beta-blocker, then ACEI
LVH/ heart failure
: diuretic w/ ACEI then beta- blocket
Which 3 beta-blockers are used for CHF?
CBM: carvedilol, bisoprolol, metoprolol (long-acting)
Which 2 beta blockers also have alpha- blocking activity?
Carvedilol and labetalol
Name an alpha-2 agonist
Clonidine (acts centrally in brain reducing sympathetic tone)
Which beta blocker is nonselective?
Which beta blockers are cardioselective?
Man: metoprolol, atenolol, nebivolol,