Anaphylaxis MEDIC12

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Initial Exposure

1st time exposed to an antigen
Sensitization

during initial exposure, wh/ may last several days, body is sensitied to an antigen
Anaphylaxis

an exagerated response to an antigen. it must be systemic & impact the airway
Allergic Reaction

the response of the body to an antigen
SRS-A
- slow reacting substance of anaphylaxis
- potent bronchoconstrictor & inflammatory agent released by mast cells; an important mediator of allergic bronchial asthma
ECF
- eosinphil chemotactic factor
- substrate released from mast cells & basophils during anaphylaxis which attracts eosinophils. a tetrapeptide mediator of immediate hypersensitivity.
Immunity

when the body does not respond to common antigens with an alergic response
What is the primary cause of death from anaphylaxis due to? (what system failure)

laryngeal edema & acute bronshospasm w/ respiratory failure (account for > 70%)
What is the secondary cause of death from anaphylaxis from? (what system failure)

circulatory collapse (accounts for 25%)