Cancer & HIV meds

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  1. What is the most common antiemetic drug for chemotherapy which is given before or after tx?
    Serotonin (Zofran)
  2. Post operative nausea associated with general anesthesia. Also a sedative/hypnotic.
    Phenergran (Promethazine)
  3. This is primarily used for motion sickness and also a histamine. (vertigo)
    Antivert (Meclizine)
  4. Primarily used as an antihistamine. Also used as an antiemetic, antiparkinsons, and antitussive.
  5. This is an ABX used for gram + and sometimes gram - bacteria.
  6. A bronchodialtor & vasoconstrictor
  7. What type of drug is aminophylline?
  8. This is used as a cardiac stimulant for V-Fib and Arrhythmias.
  9. This is used to improve muscle strength and prevens the breakdown of acetylcholine.
  10. The other name for neostigamide?
  11. What is Prostigmin used for?
  12. S/E for Neostigimide Bromide
    abd cramps, n/v, diarrhea, and increase saliva
  13. What is the other name for Sertraline?
  14. What are the S/E for Zoloft?
    insomnia, dry mouth, fatigue
  15. What is serotonin syndrome?
    Body has too much serotonin s/s are loss of coordination & rapid changes in bp
  16. What do SSRI drugs do?
    Block the reabsorption of serotonin in the brain & are selective because they only affect the serotonin neurotransmitter
  17. Describe what active immunization.
    The administering of an antigen usually a vaccine that will stimulate the body to produce antibodies.
  18. S/E for Hep B IM
    • Urticaria
    • Angioedema
    • Tenderness @ site
    • Erythemia
    • Angioedema
    • Stiffness @ site
  19. Admin 1st dose w/in 6 days of exposure, re-admin q 6 months as long as risks exists, use buttocks, make be useful for prevention of rubella.
    Immune globulin, Gamma Globulin (IM)
  20. S/E of Immunosuppressant Drugs
    • Vaginal or UTI infxn
    • CNS toxicity
    • Cough
    • Anorexia or weight gain
    • Infxn
    • Diarrhea
  21. Chloroquine
    antimalarial drug for tx of RA & discoid lupus
  22. Hydroxychloroquine
    antimalarial, long term suppresses antigens that produce RA symptoms
  23. These are used for inflammation and suppresses the immune system.
    corticosteroid drugs
  24. Are used in immunosuppression in tx of RA which decreases rheumatoid factor.
    chelating agents (penicillamine)
  25. Exert their lethal effects by interfering w/ the cell cycle of both normal and malignant cells.
    Antineoplastic drugs
  26. These are very caustic and can can extravasation which is leakage of fluid from the vein during infusion.
  27. What do you do if extravasation occurs?
    STOP drug immediately and flush w/ normal saline and then contact MD
  28. What is the other name for Cytoxan?
  29. This is a alkalating agent & antineoplastic
  30. This drug causes toxicity to hematopoietic or blood forming systems.
  31. This drug is potentially teratogenic & avoid during pregnancy and four months after.
  32. What is the other name for Procrit?
  33. How is Epoetin given?
    IV or SQ
  34. This is a synthetic version of erythropoietin that stimulates the bone marrow to produce RBCs
  35. Is Procrit used after or before chemotherapy?
    After for pts w/ significant low RBCs
  36. What is the other name for Filgrastim?
  37. How is Neupogen administered?
    IV or SQ
  38. What does Filgrastim do?
    increases neutrophils killed through chemo
  39. Used for chronic neutropenia for pre-transplant pts undergoing chemo and radiation
  40. What is the other name for Pegfilgrastim?
  41. How is Neulastia administered?
    SQ 6mg given once during chemo & store in fridge
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Cancer & HIV meds
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