Card Set Information
Name three steroid hormones.
Anabolic steroids are synthetic derivatives of testosterone.
What is androgenic?
Androgenic activity is primarily involved with the development and maintenance of masculine traits and the male reproductive system
What is anabolic?
Anabolic activity is thought to promote a more generalized growth of tissue by stimulating protein synthesis
True or False
One compound cannot contain only anabolic or androgenic activity; it will contain both.
What two organizations were the first in the US to ban steroid use?
The International Olympic Committee(IOC) and the United States Olympic Committee(USOC)
Name four reasons one would use steroids.
increase muscle development and strength
stunt growth of gymnasts
In what year did steroids get placed on the Federal Controlled Substances list?
In what year did Alabama control steroids?
What schedule are steroids(currently)?
Why did the control of steroids pose a problem to analysts?
completly new type of drug with no analytical scheme.
All steroid structures contain a five-member cyclopentane ring fused to a fully reduced phenanthrene ring system.
Beta-substituents are oriented_________________________.
Alpha-substituents are oriented_________________________.
All of the steroid hormones are biosynthesized from_______________________.
cholesterol which is obtained either from the diet or by hepatic biosynthesis
What are the two female sex hormones?
Name three legitimate uses for anabolic steroids.
treatment of hereditary anemias
as adjuncts in therapy of certain breast cancers
Where do most steroids that distributed come from?
the term used to refer to oily solutions of steroids.
the term used to refer to the intramuscular injection of anabolic steroids.
a term used to describe the desired effect of the steroid
a process which involves adding androgenic/anabolic agents.
starting at a low dose and building to a higher dose, then tapering to a lower dose before stopping use of the steroid.
involves taking drug holidays between periods of drug use.
List three negative effects on females.
hoarsening of the voice
increased facial hair
increased body hair
decreased breast size.
List three negative effects on males.
reduced sperm count
gynecomastia ; breast enlargement
alopecia ; loss of scalp hair
How do steroids stunt the growth of young users?
premature epiphyseal closure,fusion of the end portion(the epiphysis) of a long bone with the rest of the bone.
When this fusion takes place, growth is halted and normal height is not attained.
What is “Roid Rage”?
Increased aggressiveness–a sought after effect–that is frequently reported by steroids users
manifested in increased irritability, argumentativeness, hostility and combativeness
True or False
There are no withdrawal effects upon cessation of use of steroids
Name two methods of introducing steroids into the body.
IV and IM injections
True or False
Human growth hormone (HGH) is a controlled substance.
What is the schedule of GHB?
What two tests are typically done for a drug screen?
IRA and GC/MS
The ratio of_________to______exceeding_____to______indicates a positive urine screen.
How long are steroids detectable after cessation of use(for both oral and IM administration)?
oral: 2-14 days after use
IM: at least a month
What are the two best analytical methods used to ID steroids?
A base peak of______on the MS is characteristic of testosterone.