speig.txt

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Author:
emm64
ID:
142140
Filename:
speig.txt
Updated:
2012-03-17 18:20:53
Tags:
Speig Lung Renal
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Description:
Speig Lung renal
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  1. ´╗┐ACE Inhibitors
    • -pril ending
    • Captopril
    • Enalapril
    • HTN, CHF (dec mortality)
    • bad: cough(bradykinin), hyperkalemia
    • bradykinin(vasodialator) usually broken down by ACE
  2. AT-Receptor antagonists
    • -SARTAN
    • Losartan
    • AT1 receptor inhibitor
    • no "bradykinin" effects
  3. Renin Inhibitors
    aliskirin
  4. Sites of action of drugs that relax vascular smooth muscle
  5. Gingival hyperplasia:
    • nifedipine (Ca2+ channel blocker)
    • cyclosporin (immune suppressant, transplants)
  6. HTN implications for dentistry
    • Care in use of vasoconstrictors
    • (e.g. supersensitivity to catecholamines with guanethidine)
    • Orthostatic hypotention
    • (common to all antihypertensive drugs)
    • Judicious use of CNS depressants
    • (esp. with centrally-acting antihypertensive drugs)
    • Salivary inhibition
    • (xerostomia common with centrally-acting antihypertensive drugs)
    • NSAIDs
    • (decrease action of captopril, spironolactone, furosemide)
    • Gingival hyperplasia
    • (with long-term use of Ca2+channel blockers)

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