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Basics of heredity, law of segregation, law of independent assortment:
- Mendel 1857-1866
- Garden peas
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Traits reside on chromosomes, traits sort independently since chromosomes sort independently:
- Morgan 1910
- Drosophila (fruit flies)
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Genetic info is stored in the nucleus of the cell:
- Hammerling 1930's
- Acetabularia (green algae)
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Genetic info can be transferred from one cell to another (transformation)
- Griffith 1920's
- Mice and Streptococcus *bacteria strains
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DNA is the carrier of genetic information and was the factor being transfered in Griffith's experiment:
- Avery, Macloed, McCarthy 1940's
- Removed protein from Streptocococcus
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DNA is the substance being transferred between bacteria strains
- Hershey and Chase 1952
- Bacteriophages with 32P and 35S
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DNA and RNA are made of repeating nucleotides (sugar + phosphoruous group + nitrogenous base)
Levene 1920's
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Adenine pairs with thymine or uracil (RNA) and cytosine pairs with guanine
Chargaff 1960's
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DNA is a double helix
- Franklin 1953
- X-ray diffraction
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Constructed the helical model of DNA
- Watson and Crick 1953
- semiconservative
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DNA replication is semi conservative (old strand + new strand)
- Meselson and Stahl 1958
- E.coli and 14N and 15N isotopes
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