50-60 Top Hospital Drugs.txt

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Author:
HUSOP2014
ID:
142447
Filename:
50-60 Top Hospital Drugs.txt
Updated:
2012-03-20 23:09:18
Tags:
HUSOP Top 50 60 Hospital Drugs
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Description:
name, brand, class, MOA, ROA, indication
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  1. Synagis
    • Gen: Palivizumab,
    • Class: Immunological Agent, (Mab) RSV-I,
    • RoA: IM,
    • MOA: exhibits neutralizing and fusion-inhibitory activity, Indication: Repiratory syncytial virus infection (RSV)
  2. Zofran
    • Gen: Ondansetron,
    • Class: 5-HT3 Antagonist, Antiemetic,
    • RoA: Oral,
    • MOA: blocking 5-HT3 peripherally on vagal nerve terminal in CTZ (chemoreceptor trigger zone),
    • Indication: Chemotherapy/Radiation N/V, postoperative
  3. Prilosec
    • Gen: Omeprazole
    • Class: PPI
    • RoA: Oral
    • MOA: inhibits acid secretion by covalently binding H/K ATPase pumps
    • Indication: DU, GU, GERD, erosive esophagitis, gastric hypersecretion
  4. Rocephin
    • Gen: Ceftriaxone Sodium
    • Class: Antibiotic (3rd Gen cephalosporin),
    • RoA: IV
    • MOA: inhibition of cell-wall synthesis
    • Indication: UTI, LRTI, gonorrhea,
  5. Zemuron
    • Gen: Rocuronium Bromide
    • Class: Neuromuscular Blocker, Musculoskeletal agent
    • RoA: IV
    • MOA: competes for cholinergic receptors at the motor end-plate
    • Indication: General anesthesia
  6. Alimta
    • Gen: Pemetrexed
    • Class: Antineoplastic Agent (DHFR-I), pyrrolopyrimidine
    • RoA: IV infusion
    • MOA: disrupts folate-dependent metabolic processes for cell replication
    • Indication: mesothelioma, small cell lung cancer
  7. Maxipime
    • Gen: Cefepime Hydrochloride
    • Class: Antibiotic (4th Gen Cephalosporin)(PBP)
    • RoA: IV
    • MOA: inhibits cell wall synthesis
    • Indication: Pneumonia, UTI, infections
  8. Novoseven
    • Gen: Coagulation Factor VIIA
    • Class: Hemostatic (coagulant)
    • RoA: IV
    • MOA: promotes hemostasis by complexing tissue factor activating coagulation facotrs in intrinsic pathway
    • Indication: Hemophilia, Factor VII, VIII deficiency
  9. Lantus
    • Gen: Insulin Glargine, Recombinant
    • Class: Antidiabetic (long acting insulin)
    • RoA: SC
    • MOA: Stimulates glucose uptake by muscle
    • Indication: Diabetes mellitus type 1 & 2
  10. Optiray 320
    • Gen: Ioversol
    • Class: non radial contrast agent
    • RoA: IV
    • MOA:
    • Indication: diagnostic radiology
  11. Activase
    • Gen: Alteplase, Recombinant
    • Class: Thromolytic, Tissue Plasminogen Activator (TPA)(anti-coagulant)
    • RoA: IV
    • MOA: enhances plasminogen to plasmin by binding fibrin initiating fibrinolysis,
    • Indication: Acute MI & Ischemia, PE, venous catheter occlusion

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